uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
A Prospective, Controlled, Multicenter Study to Evaluate the Clinical Outcome of Implant Treatment in Women with Osteoporosis/Osteopenia: 5-Year Results
Katholieke Univ Leuven, KU Leuven & Dent, Univ Hosp, Sect Periodontol,Dept Oral Hlth Sci, Kapucijnenvoer 7, B-3000 Leuven, Belgium.
Univ Gothenburg, Sahlgrenska Acad, Dept Oral & Maxillofacial Surg, Gothenburg, Sweden.
Univ Wurzburg, Dept Oral & Maxillofacial Plast Surg, Wurzburg, Germany.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Oral and Maxillofacial Surgery.ORCID iD: 0000-0001-9590-2039
Show others and affiliations
2019 (English)In: Journal of Dental Research, ISSN 0022-0345, E-ISSN 1544-0591, Vol. 98, no 1, p. 84-90Article in journal (Refereed) Published
Abstract [en]

The impact of osteoporosis on implant treatment is still a matter of debate in the scientific community, as it may possibly lead to higher failure rates. As long-term controlled trials are missing, the aim of this study was to verify the long-term outcome of implants placed in patients with systemic osteoporosis. Postmenopausal women in need of implants underwent bone mineral density measurements in hip and spine, using dual X-ray absorptiometry scans. Based on T-scores, they were divided into 2 groups: group O (osteoporosis group) with a T-score <=-2 or group C (control group) with a T-score of >=-1. Implants were placed in a 2-stage manner and loaded 4 to 8 wk after abutment surgery. Six months after loading and thereafter yearly, clinical and radiographical parameters were assessed. In total, 148 implants were placed in 48 patients (mean age: 67 y [range, 59-83]). Sixty-three implants were placed in 20 patients (group O) and 85 implants in 28 patients (group C). After 5 y, 117 implants (38 in group O and 79 in the group C) in 37 patients were assessed. Cumulative survival rate on an implant level was 96.5% (group O: 91.5%; group C: 100.0% [P < 0.05]) and 95.7% (group O: 89.2%; group C: 100.0% [P > 0.05]) on a patient level. The overall marginal bone-level alterations, after 5 y of loading, were -0.09 +/- 0.78 mm (group O: -0.15 +/- 0.50 mm; group C: -0.06 +/- 0.89 mm) on an implant level and -0.09 +/- 0.54 mm (group O: -0.18 +/- 0.43 mm; group C: 0.06 +/- 0.58 mm) on a patient level (P > 0.05). Oral implant therapy in osteoporotic patients is a reliable treatment option with comparable osseointegration rates, implant survival, and marginal bone-level alterations after 5 y of functional loading (ClinicalTrials.gov NCT00745121).

Place, publisher, year, edition, pages
SAGE PUBLICATIONS INC , 2019. Vol. 98, no 1, p. 84-90
Keywords [en]
dental implants, marginal bone loss, postmenopausal, long-term outcome, survival rates, bone mineral density
National Category
Dentistry
Identifiers
URN: urn:nbn:se:uu:diva-373311DOI: 10.1177/0022034518798804ISI: 000454149700012PubMedID: 30205020OAI: oai:DiVA.org:uu-373311DiVA, id: diva2:1279423
Available from: 2019-01-16 Created: 2019-01-16 Last updated: 2019-01-16Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Authority records BETA

Thor, Andreas

Search in DiVA

By author/editor
Thor, Andreas
By organisation
Oral and Maxillofacial Surgery
In the same journal
Journal of Dental Research
Dentistry

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 174 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf