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Baseline characteristics and previous medication reviews - A MedBridge sub-study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences.
2019 (English)Independent thesis Advanced level (degree of Master (One Year)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Introduction:

Medication Reviews Bridging Healthcare (MedBridge) is a three-armed cluster randomized controlled trial (C-RCT) with crossover design, aiming to evaluate the effects of pharmacist led medication reviews on patient outcomes. In all RCTs, baseline characteristics such as demographics and medical history are recorded to characterize the patients in the study. This can be used to interpret the results of the study.   

Aim:

To analyze and describe baseline patient characteristics, with focus on previous medication reviews to illustrate study groups in the MedBridge study and to determine if the groups are well balanced.  

Materials and Methods:

Patient baseline characteristics were extracted for 699 patients from the electronic medical record system Cosmic© (Cambio Healthcare Systems AB, Stockholm, Sweden), stored in the electronic data capture system Castor EDC©, where the data was pooled with the data of all other patients in the MedBridge study. It was summarized and analyzed in Microsoft Excel©.   

Results:

The study population consisted of 2640 patients. There were no statistically significant differences of the baseline characteristics between the three study groups, including the prevalence of previous medication reviews. The mean number of medication reviews for all patients 12 months before enrolment in the study were 0.242, 0.248 and 0.225 for the three study groups, with a p value of 0.750.   

Conclusion:

The MedBridge study appears to consist of three well balanced groups, with regards to baseline characteristics, and previous medication reviews. This means that any differences in outcome between the study groups of MedBridge can be assumed to be due to differences in the interventions between the groups.

Place, publisher, year, edition, pages
2019. , p. 23
National Category
Pharmaceutical Sciences
Identifiers
URN: urn:nbn:se:uu:diva-376877OAI: oai:DiVA.org:uu-376877DiVA, id: diva2:1287767
External cooperation
Akademiska sjukhuset
Subject / course
Pharmacotherapy
Educational program
Master of Science Programme in Pharmacy
Supervisors
Examiners
Available from: 2019-02-21 Created: 2019-02-11 Last updated: 2019-02-21Bibliographically approved

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CiteExportLink to record
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