uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Sarcopenic obesity and associations with mortality- a prospective observational study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism. Dept. of Public Health and Caring Sciences/ Clinical Nutrition and Metabolism, Uppsala University.
Department of Medical Gastroenterology, Odense University Hospital, Denmark.
Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Social Sciences, Department of Food, Nutrition and Dietetics.
Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Social Sciences, Department of Food, Nutrition and Dietetics. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism.
Show others and affiliations
(English)Manuscript (preprint) (Other academic)
Keywords [en]
older adults, sarcopenic obesity, EWGSOP2, prevalence, mortality
National Category
Medical and Health Sciences
Research subject
Nutrition
Identifiers
URN: urn:nbn:se:uu:diva-377872OAI: oai:DiVA.org:uu-377872DiVA, id: diva2:1292229
Available from: 2019-02-27 Created: 2019-02-27 Last updated: 2019-02-27
In thesis
1. Nutrition, exercise and body composition in community-dwelling older adults: Effects on function, wellbeing and mortality
Open this publication in new window or tab >>Nutrition, exercise and body composition in community-dwelling older adults: Effects on function, wellbeing and mortality
2019 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Background: The demographic shift in society with more people reaching a high age provides new challenges for both society and the healthcare system.

Aim: The overall aim of this thesis was to examine the impact of nutrition, exercise and body composition on function, wellbeing and mortality in community-dwelling older adults.

The thesis is based on 1) data from the Vitality, Independence and Vigor in the Elderly 2 study (VIVE2) (Papers I-III), i.e. 149 community-dwelling participants >70 years who took part in an exercise program, and were randomized to take either a protein- and vitamin D-rich supplement or a placebo for 6 months and 2) three cohorts from two Swedish population studies on older adults (Paper IV). Quantitative (Papers I, II and IV) and qualitative methods (Paper III) were used. Results: Paper I reports cross-sectional data showing that there was no clear association between serum levels of serum 25(OH)D and physical performance in mobility-limited adults.

In Paper II, the results of the VIVE2 study indicated positive effects on mental health from exercise but no additional effect from supplementation was detected.

In Paper III, the qualitative interview investigation indicated that the VIVE2 intervention had positive effects, both psychologically and physically. Another finding was that weight loss was a main reason for participants wanting to take part in the study, whereas the aim of the study was to improve muscle function.

Paper IV shows from prospective observational data that 75-year-old women with sarcopenic obesity had an increased mortality risk within 10 years, while a similar result could not be found among 75-year-old or 88-year-old men.

Conclusion: The exercise intervention improved the mental status of the participants based on both quantitative and qualitative studies. No effect could be attributed to the protein- and vitamin D-rich nutritional supplement, a finding that needs to be evaluated in light of the participants’ good nutritional status. No clear association was revealed between physical function and serum 25(OH)D. Sarcopenic obesity may be associated with mortality but such associations may depend on age and gender.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2019. p. 81
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 1651-6206 ; 1545
Keywords
Older adults, function, nutrition, wellbeing, mortality, exercise, sarcopenic obesity
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-377873 (URN)978-91-513-0584-4 (ISBN)
Public defence
2019-04-17, Sal A1:111a, Biomedicinsk Centrum (BMC), Husargatan 3, Uppsala, 09:00 (Swedish)
Opponent
Supervisors
Available from: 2019-03-27 Created: 2019-02-27 Last updated: 2019-05-07

Open Access in DiVA

No full text in DiVA

Authority records BETA

von Berens, ÅsaNydahl, MargarethaKoochek, AfsanehCederholm, Tommy

Search in DiVA

By author/editor
von Berens, ÅsaNydahl, MargarethaKoochek, AfsanehCederholm, Tommy
By organisation
Clinical Nutrition and MetabolismDepartment of Food, Nutrition and DieteticsGeriatrics
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

urn-nbn

Altmetric score

urn-nbn
Total: 7 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf