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Angular distribution of Pigment epithelium central limit-Inner limit of the retina Minimal Distance (PIMD), in the young not pathological  optic nerve head imaged by OCT
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience. (Per Söderberg)ORCID iD: 0000-0002-7157-2802
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Ophthalmology. Center for Research and Development, Region Gävleborg. (Per Söderberg)
2018 (English)In: SPIE Proc, Vol. 10474, p. 38:1-38:7Article in journal (Refereed) Published
Abstract [en]

The present study aimed to elucidate the angular distribution of the Pigment epithelium central limit-Inner limit of the retina Minimal Distance measured over 2π radians in the frontal plane (PIMD-2π) in young healthy eyes. Both healthy eyes of 16 subjects aged [20;30[ years were included. In each eye, a volume of the optical nerve head (ONH) was captured three times with a TOPCON DRI OCT Triton (Japan). Each volume renders a representation of the ONH 2.8 mm along the sagittal axis resolved in 993 steps, 6 mm long the frontal axis resolved in 512 steps and 6 x mm along the longitudinal axis resolved in 256 steps. The captured volumes were transferred to a custom made software for semiautomatic segmentation of PIMD around the circumference of the ONH. The phases of iterated volumes were calibrated with cross correlation. It was found that PIMD-2π expresses a double hump with a small maximum superiorly, a larger maximum inferiorly, and minima in between. The measurements indicated that there is no difference of PIMD-2π between genders nor between dominant and not dominant eye within subject. The variation between eyes within subject is of the same order as the variation among subjects. The variation among volumes within eye is substantially lower.

Place, publisher, year, edition, pages
2018. Vol. 10474, p. 38:1-38:7
National Category
Ophthalmology
Identifiers
URN: urn:nbn:se:uu:diva-384738DOI: 10.1117/12.2299723OAI: oai:DiVA.org:uu-384738DiVA, id: diva2:1321425
Available from: 2019-06-07 Created: 2019-06-07 Last updated: 2019-08-21Bibliographically approved

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Söderberg, PerSandberg Melin, Camilla

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