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Amplitude-integrated electroencephalography for seizure detection in newborn infants
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Research group (Dept. of women´s and children´s health), Perinatal, Neonatal and Pediatric Cardiology Research. Univ Hosp, SE-75185 Uppsala, Sweden.
2018 (English)In: Seminars in Fetal & Neonatal Medicine, ISSN 1744-165X, E-ISSN 1878-0946, Vol. 23, no 3, p. 175-182Article in journal (Refereed) Published
Abstract [en]

The amplitude-integrated electroencephalogram (aEEG) is a filtered and compressed EEG trend that can be used for long-term monitoring of brain function in patients of all ages. aEEG is increasingly used in neonatal intensive care units since several studies have shown its utility in high-risk newborn infants. Main indications for aEEG monitoring include early evaluation of brain function after perinatal asphyxia and seizure detection. The aEEG is usually recorded from one or two channels derived from parietal, central, or frontal leads. Although the aEEG is very useful for identifying high-risk infants and infants with seizures, the compressed trend has limitations with regards to detection of individual seizures. However, modern monitors also display the corresponding EEG (aEEG/EEG), which increases the probability of detecting single brief seizures. For improved evaluation of electrocortical brain activity the aEEG/EEG should be assessed together with repeated conventional EEGs or multi-channel EEG monitoring in a multi-disciplinary team.

Place, publisher, year, edition, pages
2018. Vol. 23, no 3, p. 175-182
Keywords [en]
Brain monitoring, Electroencephalography, Antiepileptic treatment, Neonatal encephalopathy, Intraventricular hemorrhage, White matter damage
National Category
Pediatrics
Identifiers
URN: urn:nbn:se:uu:diva-387457DOI: 10.1016/j.siny.2018.02.003ISI: 000439674400004PubMedID: 29472139OAI: oai:DiVA.org:uu-387457DiVA, id: diva2:1330367
Available from: 2019-06-25 Created: 2019-06-25 Last updated: 2019-06-25Bibliographically approved

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Hellström-Westas, Lena

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