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Dose estimation of ultra-low-dose chest CT to different sized adult patients
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Research and Development, Gävleborg.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences.
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Organismal Biology, Systematic Biology.
2019 (English)In: European Radiology, ISSN 0938-7994, E-ISSN 1432-1084, Vol. 29, no 8, p. 4315-4323Article in journal (Refereed) Published
Abstract [en]

Objectives: To evaluate the effect of patient size on radiation dose for standard CT (SD-CT), ultra-low-dose CT (ULD-CT) and two-view digital radiography (DR).

Methods: Dosimeters were distributed within the lungs of chest phantoms representing males of 65kg and 82kg (body mass indices 23 and 29). In contrast to SD-CT and DR which include automatic exposure control (AEC), the ULD scan employs a fixed mAs value. The phantoms were exposed to SD, ULD and DR while recording lung doses. Projected dose data were calculated from the phantoms. The resulting exposure settings were used in Monte Carlo programs to determine the effective dose for a standard-sized (BMI 24.2) adult male (170cm/70kg) and female (160cm/59kg). Patients previously examined by both ULD- and SD-CT were identified to determine post hoc size-specific dose estimates (SSDEs).

Results: ULD-CT dose was inversely related to patient size; average lung doses summarised in terms of patient size BMI23/29 are 5.2/8.1 (SD-CT), 0.56/0.35 (ULD-CT) and 0.05/0.13mGy (DR), while the effective doses for these techniques on a standard-sized male were 2.9, 0.16 and 0.03mSv and 2.3, 0.247 and 0.024mSv for a standard-sized female respectively. SSDEs for 15 patients (averages: BMI 26, range 18-37) averaged 5.5mGy (3.6-10) for SD-CT and 0.35mGy (0.42-0.27) for ULD-CT.

Conclusions: The effective doses for a standard-sized male and female examined by ULD-CT are (respectively) 6%/11% of SD-CT and 5/10 times higher than DR. ULD-CT gave a lower radiation dosage to larger patients than DR. AEC is warranted in ULD-CT for improved dose consistency.

Key Points: center dot For standard-sized patients, ULD-CT dose level is 6%/11% of SD-CT, and 5/10 times higher than DR. For larger patients, ULD-CT is currently being used clinically at lower dose levels than DR.center dot Using ULD-CT should greatly reduce the risk of late effects from ionising radiation.center dot AEC in ULD-CT is desirable for increased consistency in patient dose.

Place, publisher, year, edition, pages
SPRINGER , 2019. Vol. 29, no 8, p. 4315-4323
Keywords [en]
Tomography, Thoracic radiography, Digital radiography, Radiation dosage
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:uu:diva-390508DOI: 10.1007/s00330-018-5849-5ISI: 000473737100039PubMedID: 30560356OAI: oai:DiVA.org:uu-390508DiVA, id: diva2:1341883
Conference
Congress of the European-Society-of-Radiology (ECR), FEB 28-MAR 04, 2018, Vienna, AUSTRIA
Available from: 2019-08-12 Created: 2019-08-12 Last updated: 2019-08-12Bibliographically approved

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Ast, Jennifer C.

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