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Trapping of cell-laden hyaluronic acid-acrylamide hydrogel droplets using bulk acoustic waves
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology. Uppsala University, Science for Life Laboratory, SciLifeLab. (Embla)ORCID iD: 0000-0001-7980-376X
Lund University, Lund, Sweden.
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology. Uppsala University, Science for Life Laboratory, SciLifeLab. National University of Singapore, Singapore.ORCID iD: 0000-0001-9102-956x
Lund University, Lund, Sweden.
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2019 (English)Conference paper, Poster (with or without abstract) (Refereed)
Abstract [en]

In this paper an acoustofluidic system to trap hydrogel droplets is shown. The presented trapping method is label-free, biocompatible and operated in non-contact mode. The results show that the droplets can be trapped at flow rates up to 76 µL/min which corresponds to an average flow speed of 3.2 mm/s. Moreover, it is shown that the droplets can be trapped for several hours, thus allowing for studies of the encapsulated cells over time. An application of the system is shown by performing on-chip cell nuclei staining. 

Place, publisher, year, edition, pages
2019.
Keywords [en]
Acoustofluidics, droplet microfluidics, hydrogels, particle manipulation
National Category
Engineering and Technology Physical Sciences
Research subject
Engineering Science with specialization in Microsystems Technology
Identifiers
URN: urn:nbn:se:uu:diva-390926OAI: oai:DiVA.org:uu-390926DiVA, id: diva2:1343184
Conference
Transducers 2019 - EUROSENSORS XXXIII, 23-27 June 2019, Berlin, Germany
Available from: 2019-08-15 Created: 2019-08-15 Last updated: 2019-08-15Bibliographically approved

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Fornell, AnnaSearle, SeanTenje, Maria

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