uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
The clinical application of gene editing: ethical and social issues
Stanford Univ, Sch Med, Dept Genet, Stanford, CA 94305 USA;Stanford Univ, Sch Med, Stanford Ctr Biomed Eth, Stanford, CA 94305 USA.
Univ Toronto, Inst Hlth Policy Management & Evaluat, Toronto, ON, Canada;St Michaels Hosp, Li Ka Shing Knowledge Inst, Toronto, ON, Canada.
NHGRI, Social & Behav Res Branch, NIH, Bethesda, MD 20892 USA.
Penn Med, Penn Ctr Inherited Cardiac Dis, Philadelphia, PA 19104 USA.
Show others and affiliations
2019 (English)In: Personalized Medicine, ISSN 1741-0541, E-ISSN 1744-828X, Vol. 16, no 4, p. 337-350Article in journal (Refereed) Published
Abstract [en]

Gene-editing techniques have progressed rapidly in the past 5years. There are already ongoing human somatic gene-editing clinical trials for multiple diseases. And there has been one purported scenario of human germline gene editing in late 2018. In this paper, we will review the current state of the technology, discuss the ethical and social issues that surround the various forms of gene editing, as well as review emerging stakeholder data from professionals, the general public' and individuals and families dealing with genetic diseases potentially treatable by gene editing.

Place, publisher, year, edition, pages
2019. Vol. 16, no 4, p. 337-350
Keywords [en]
clinical trials, CRISPR, ethics, gene editing, genome editing, germline gene editing, professional attitudes, public attitudes, somatic gene editing, stakeholder research
National Category
Medical Ethics
Identifiers
URN: urn:nbn:se:uu:diva-393137DOI: 10.2217/pme-2018-0155ISI: 000479005800008PubMedID: 31331245OAI: oai:DiVA.org:uu-393137DiVA, id: diva2:1353758
Funder
Swedish Research Council, 2017-01710Available from: 2019-09-24 Created: 2019-09-24 Last updated: 2019-09-24Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Authority records BETA

Howard, Heidi Carmen

Search in DiVA

By author/editor
Howard, Heidi Carmen
By organisation
Centre for Research Ethics and Bioethics
In the same journal
Personalized Medicine
Medical Ethics

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 14 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf