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Imaging the Injured Lung: Mechanisms of Action and Clinical Use
Univ Penn, Dept Anesthesiol & Crit Care, Philadelphia, PA 19104 USA;Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA.
Univ Penn, Dept Anesthesiol & Crit Care, Philadelphia, PA 19104 USA;Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA.
Univ Toronto, Interdept Div Crit Care Med, Toronto, ON, Canada;Univ Toronto, Dept Med, Toronto, ON, Canada.
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2019 (English)In: Anesthesiology, ISSN 0003-3022, E-ISSN 1528-1175, Vol. 131, no 3, p. 716-749Article, review/survey (Refereed) Published
Abstract [en]

Acute respiratory distress syndrome (ARDS) consists of acute hypoxemic respiratory failure characterized by massive and heterogeneously distributed loss of lung aeration caused by diffuse inflammation and edema present in interstitial and alveolar spaces. It is defined by consensus criteria, which include diffuse infiltrates on chest imaging-either plain radiography or computed tomography. This review will summarize how imaging sciences can inform modern respiratory management of ARDS and continue to increase the understanding of the acutely injured lung. This review also describes newer imaging methodologies that are likely to inform future clinical decision-making and potentially improve outcome. For each imaging modality, this review systematically describes the underlying principles, technology involved, measurements obtained, insights gained by the technique, emerging approaches, limitations, and future developments. Finally, integrated approaches are considered whereby multimodal imaging may impact management of ARDS.

Place, publisher, year, edition, pages
LIPPINCOTT WILLIAMS & WILKINS , 2019. Vol. 131, no 3, p. 716-749
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Anesthesiology and Intensive Care
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URN: urn:nbn:se:uu:diva-395360DOI: 10.1097/ALN.0000000000002583ISI: 000484161900034PubMedID: 30664057OAI: oai:DiVA.org:uu-395360DiVA, id: diva2:1362902
Available from: 2019-10-22 Created: 2019-10-22 Last updated: 2019-10-22Bibliographically approved

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Perchiazzi, Gaetano

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