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Remediating reduced memory specificity in bipolar disorder: A case study using a Computerized Memory Specificity Training.
Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Social Sciences, Department of Psychology. (EMIL)ORCID iD: 0000-0001-7319-3112
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2019 (English)In: Brain and Behavior, ISSN 2162-3279, E-ISSN 2162-3279, Vol. 9, no 12, article id e01468Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: Reduced autobiographical memory specificity (rAMS) is a vulnerability factor found across unipolar depression (UD), posttraumatic stress disorder (PTSD), eating disorder, schizophrenia, and bipolar disorder (BD). A group delivered psychological therapy training called Memory Specificity Training (MeST) remediates rAMS in UD and PTSD, with additional downstream effects on related psychological processes and symptoms. Its impact in BD is unknown. In this case study, we examined the impact of a computerized version of MeST (c-MeST) on improving AMS and related symptoms and processes in participant with rapid cycling type I BD.

METHOD: An experimental case study with an ABA design was used. During baseline (14 days, Phase A), the training phase (nine sessions across 17 days, Phase B), and a 1-month follow-up (Phase A), memory specificity, depressive symptoms, and related processes and symptoms were repeatedly measured.

RESULTS: Memory specificity increased significantly after the participant completed c-MeST. Session-to-session scores indicated that AMS improved most from the in-person baseline assessment to the first online session. All other measures of processes and symptoms deteriorated during the training phase but regressed to baseline during follow-up.

CONCLUSION: Memory specificity was improved as indicated by increased AMS from pre-intervention measurement to 1-month follow-up. Other improvements in symptoms were not observed. Rather, some related maladaptive psychological processes and symptoms worsened during the training phase and regressed to baseline during follow-up.

Place, publisher, year, edition, pages
2019. Vol. 9, no 12, article id e01468
Keywords [en]
Memory Specificity Training, autobiographical memory, bipolar disorder, reduced autobiographical memory specificity
National Category
Psychology
Research subject
Psychology
Identifiers
URN: urn:nbn:se:uu:diva-401942DOI: 10.1002/brb3.1468PubMedID: 31747124OAI: oai:DiVA.org:uu-401942DiVA, id: diva2:1384448
Available from: 2020-01-09 Created: 2020-01-09 Last updated: 2020-02-17Bibliographically approved

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Holmes, Emily A.

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