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[Whipple's disease: very rare, fatal without treatment but easily cured].
Gavle sjukhus - Klinisk patologi och cytologi Gavle, Sweden Gavle sjukhus - Gastroenterologmottagning Gavle, Sweden..
2019 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 116, article id FLMUArticle in journal (Refereed) Published
Abstract [sv]

Whipple's disease is a chronic infectious disease that primarily affects the small intestine, but several organs can be involved simultaneously. The disease is caused by a gram-positive bacterium called Tropheryma whipplei. The disease is difficult to suspect because it is rare, and produces unspecific and long-term symptoms. Whipple's disease can lead to death if not treated. We here present a case of a man who presented with gastrointestinal symptoms in the form of diarrhea with blood, weight loss, fever, and lymphadenopathy and who was finally diagnosed with Whipple's disease 4 years after the occurrence of manifestations from the joints. The diagnosis was made both with 16S rRNA against Tropheryma whipplei and histopathologically from biopsy taken from the duodenum and distal ileum. The purpose of this case report is to raise awareness of a very rare disease that presented with a combination of symptoms similar to other and significantly more common diseases.

Place, publisher, year, edition, pages
2019. Vol. 116, article id FLMU
National Category
Clinical Laboratory Medicine
Research subject
Pathology
Identifiers
URN: urn:nbn:se:uu:diva-401988PubMedID: 31192432OAI: oai:DiVA.org:uu-401988DiVA, id: diva2:1384647
Available from: 2020-01-10 Created: 2020-01-10 Last updated: 2020-02-05Bibliographically approved

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