uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Identifying patients who benefit the most from a medication review — a MedBridge sub-study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences.
2020 (English)Independent thesis Advanced level (degree of Master (One Year)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Introduction: Comprehensive medication reviews (CMRs) have been introduced to improve patient’s medication treatment by identifying drug-related problems (DRPs) and taking actions to solve these DRPs. It is unclear how to prioritise patients who will benefit most from a CMR. The aim of this study was to identify patient characteristics that correlate with the number of identified DRPs and actions taken, in order to prioritise patients in need of a CMR.

Method: Patients aged ≥ 65 years who had received a CMR in an ongoing cluster-randomised controlled trial in Sweden (the MedBridge trial) were included in this study. Baseline characteristics on age, medication use, medical history, social situation, automated drug dispensing, previous medication reviews and data about identified DRPs and actions taken were collected from the patients’ electronic health records. Multivariable linear regression with both number of DRPs and actions as dependent variable were conducted with all characteristics that were statistically significant in univariable analysis.

Result: In total, 652 patients (mean age 81 years; 47% male) were included. On average 9.5 (SD 5.6) medications were used, 3.2 (SD 2.8) DRPs were identified and 2.4 (SD 2.6) actions were taken per patient. Number of medications was the only patient characteristic correlated with either the number of DRPs or actions in the multivariable regression analysis. One extra medication in use corresponded to 0.11 (95% confidence interval (CI) 0.08 – 0.14) additional DRPs and 0.08 (95% CI 0.05 – 0.11) additional actions per patient.

Conclusion: Patients ≥ 65 years old should be prioritised for a CMR based on number of medications only.

Place, publisher, year, edition, pages
2020. , p. 62
National Category
Pharmaceutical Sciences
Identifiers
URN: urn:nbn:se:uu:diva-404559OAI: oai:DiVA.org:uu-404559DiVA, id: diva2:1396983
Subject / course
Pharmacotherapy
Educational program
Master of Science Programme in Pharmacy
Supervisors
Examiners
Available from: 2020-02-27 Created: 2020-02-27 Last updated: 2020-02-27Bibliographically approved

Open Access in DiVA

No full text in DiVA

By organisation
Department of Pharmaceutical Biosciences
Pharmaceutical Sciences

Search outside of DiVA

GoogleGoogle Scholar

urn-nbn

Altmetric score

urn-nbn
Total: 4 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf