Efficient Route to the Pineal Hormone Melatonin by Radical-Based Indole Synthesis
2003 (English)In: Synthetic Communications, ISSN 0039-7911, E-ISSN 1532-2432, Vol. 33, no 20, 3631-3641 p.Article in journal (Refereed) Published
The hormone melatonin, which is known to have a range of important biological effects, has been prepared in a high-yielding route that features formation of the indole nucleus by radical cyclization. Mediation of the radical cyclization by tristrimethylsilylsilane (TTMSS) is more efficient than by N-ethylpiperidine hypophosphite.
Place, publisher, year, edition, pages
2003. Vol. 33, no 20, 3631-3641 p.
IdentifiersURN: urn:nbn:se:uu:diva-90419DOI: 10.1081/SCC-120024751OAI: oai:DiVA.org:uu-90419DiVA: diva2:162768