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The structure of posttraumatic stress symptoms: A model fitting approach
Uppsala University, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Faculty of Social Sciences, Department of Psychology.
Manuscript (Other academic)
Identifiers
URN: urn:nbn:se:uu:diva-90687OAI: oai:DiVA.org:uu-90687DiVA: diva2:163133
Available from: 2003-09-05 Created: 2003-09-05 Last updated: 2010-01-13Bibliographically approved
In thesis
1. Posttraumatic Stress Disorder (PTSD) in the General Population
Open this publication in new window or tab >>Posttraumatic Stress Disorder (PTSD) in the General Population
2003 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

This thesis explored the epidemiology of Posttraumatic Stress Disorder (PTSD) and different aspects of the disorder. Firstly, we investigated the lifetime prevalence of traumatic experiences and PTSD in the general adult population in Sweden and evaluated the impact of different trauma types, trauma frequency, and perceived distress. The results show that traumatic experiences are common and PTSD is not rare; roughly one out of ten traumatic events results in PTSD, with a 5.6% lifetime prevalence. The female/male ratio is 2:1. The risk for PTSD increases considerably with a high trauma-associated emotional impact. The distressing impact of a given trauma appears to be higher in women than in men, indicating an increased vulnerability in women. Secondly, we hypothesized that traffic road accidents (TRA’s) are one of the most prevalent types of traumatic events in Swedish society; therefore, we examined the impact of event and response characteristics associated with TRA’s on PTSD development. The data demonstrate that of those who had experienced a TRA (n=1074, 58.9%), 6.1% reported lifetime PTSD. TRA’s associated with fatal accidents and injury to oneself and related to high distress more than double the risk for PTSD. Thirdly, we compared the relative merits of the DSM-IV’s three-factor solution for PTSD symptoms to alternative models. We found that the symptomatology is equally well accounted for using all factor analytic models as yet presented in the literature; the DSM-IV, we found, provides as good a fit to data as other models. Fourthly, we examined the neurofunctional correlates of PTSD symptoms and whether a treatment-induced (serotonin reuptake inhibitor - SSRI) reduction of PTSD symptoms is associated with altered rCBF during symptom provocation. Our results indicate that PTSD symptoms correlates with areas involved in memory, emotion, attention, and motor control and that SSRI treatment normalizes provocation-induced rCBF in these areas.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2003. 66 p.
Series
Comprehensive Summaries of Uppsala Dissertations from the Faculty of Social Sciences, ISSN 0282-7492 ; 129
Keyword
Psychology, posttraumatic stress disorder, trauma, epidemiology, general population, prevalence, traffic road accidents, DSM-structure, positron emission tomography, regional cerebral blood flow, symptom provocation, selective serotonin reuptake inhibitor, Psykologi
National Category
Psychology
Research subject
Clinical Psychology
Identifiers
urn:nbn:se:uu:diva-3528 (URN)91-554-5697-9 (ISBN)
Public defence
2003-10-03, Sal IX, Universitetshuset, Uppsala, 09:15
Opponent
Supervisors
Available from: 2003-09-05 Created: 2003-09-05Bibliographically approved

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