Arylboronic acids as versatile coupling partners in fast microwave promoted oxidative Heck chemistry
2003 (English)In: Molecular diversity, ISSN 1381-1991, E-ISSN 1573-501X, Vol. 7, no 2-4, 97-106 p.Article in journal (Refereed) Published
The useful and selective reactivity of arylboronic acids makes them favourite building blocks for many modern organic chemistry applications like the metal-mediated formation of C-C, C-O, C-N, and C-S bonds. This report describes oxidative Heck coupling reactions of arylboronic acids and olefins, which were conveniently and rapidly (5-30 min) carried out under air with temperature-controlled microwave heating. Different reaction conditions were investigated with regard to both microwave heating capability and chemical productivity. Copper(II) acetate was identified as a microwave compatible reoxidant of Pd(0). The scope and limitations of this high-speed chemistry protocol with diverse olefins and organoboronic acids are discussed.
Place, publisher, year, edition, pages
2003. Vol. 7, no 2-4, 97-106 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-90947DOI: 10.1023/B:MODI.0000006803.99656.8cPubMedID: 14870838OAI: oai:DiVA.org:uu-90947DiVA: diva2:163477