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Screening for retinopathy of prematurity: evaluation and modification of guidelines
Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Neuroscience, Ophthalmology.
2002 In: British Journal of Ophthalmology, Vol. 86, no 12, 1399-1402 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2002. Vol. 86, no 12, 1399-1402 p.
URN: urn:nbn:se:uu:diva-91346OAI: oai:DiVA.org:uu-91346DiVA: diva2:164046
Available from: 2004-02-26 Created: 2004-02-26Bibliographically approved
In thesis
1. Short- and Long-Term Follow-Up of Ophthalmological Findings in Preterm Infants and Children
Open this publication in new window or tab >>Short- and Long-Term Follow-Up of Ophthalmological Findings in Preterm Infants and Children
2004 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

In a prospective population-based study in Stockholm County, 1998-2000, the incidence of retinopathy of prematurity (ROP) was investigated and was found to be 36% in prematurely-born infants with a birth weight of ≤ 1500 grams. Compared to a study performed ten years ago, the overall incidence was unchanged, but was reduced in “mature” infants and increased in immature ones. The incidence of ROP was 25% in infants with a gestational age of ≤ 32 weeks at birth. The main risk factors for ROP were the gestational age at birth, followed by the birth weight. Current guidelines for ROP screening in Sweden were modified.

A 10-year follow-up study of the ophthalmological findings in prematurely-born children, previously included in a prospective population-based incidence study of ROP, was performed. The children were compared with full-term ones.

Prematurely-born children ran a four times higher risk of refractive errors than full-term ones. The cryotreated children had the highest risk, but those without ROP also had more refractive errors than the full-terms. Within the group of prematurely-born children, the cryotreated ones had the highest prevalence of myopia, astigmatism and anisometropia, but no difference was found regarding hypermetropia.

The visual acuity of prematurely-born children was poorer than that of the full-terms. The cryotreated children and those with neurological complications had the most marked reduction, but the children without ROP and neurological findings also had a poorer visual outcome than the full-terms. The prevalence of visual impairment was 1.8% among the prematurely-born children, and was due to ROP in half the cases and cerebral lesions in the others.

The cryotreated children had constricted peripheral visual fields compared to the untreated prematurely-born and full-term children. The central visual fields tended to be reduced in the prematurely-born children compared to the full-terms, but no difference was observed within the preterm group.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2004. 61 p.
Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 0282-7476 ; 1323
Ophtalmology, prematurity, follow-up, retinopathy of prematurity, ROP, infants, children, incidence, screening, refraction, visual acuity, visual fields, Oftalmiatrik
National Category
urn:nbn:se:uu:diva-3994 (URN)91-554-5871-8 (ISBN)
Public defence
2004-03-19, Aulan, Entrance 50, Akademiska sjukhuset, Uppsala, 09:15
Available from: 2004-02-26 Created: 2004-02-26Bibliographically approved

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