uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Single microgel particle studies demonstrate the influence of hydrophobic interactions between charged micelles and oppositely charged polyions.
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Physical and Analytical Chemistry, Physical Chemistry I.
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Physical Chemistry.
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Physical and Analytical Chemistry, Physical Chemistry I.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacy.ORCID iD: 0000-0002-0895-1180
2005 (English)In: Langmuir, ISSN 0743-7463, E-ISSN 1520-5827, Vol. 21, no 9, 3773-3781 p.Article in journal (Refereed) Published
Abstract [en]

The binding of two cationic surfactants, dodecyltrimethylammonium bromide (DoTAB) and N-(1,1,2,2-tetrahydroperfluorodecanyl)pyridinium bromide (HFDePB), to covalently cross-linked sodium poly(styrenesulfonate) (PSS) microgels has been investigated by means of micromanipulator-assisted time-resolved light microscopy on single gels. It is demonstrated that repeated measurements on the same microgel under conditions of controlled liquid flow give highly reproducible results. The two surfactants are found to behave very differently with respect to degree of swelling, surfactant distribution in the gels, both during shrinking and at equilibrium, and kinetics of volume changes induced by them. The main difference is attributed to the presence of a hydrophobic interaction between PSS and the DoTAB micelles, absent in the case of HFDePB. Kinetic shrinking curves are recorded and analyzed using a model for steady-state transport of surfactant between the solution and the gels. Aggregation numbers for DoTAB in PSS solutions obtained from fluorescence quenching measurements are presented. A strong dependence on the surfactant-to-polyion concentration ratio is observed. Relations between surfactant binding isotherms, phase diagrams for linear polyelectrolyte/surfactant/water systems, and the binding to gels are discussed.

Place, publisher, year, edition, pages
2005. Vol. 21, no 9, 3773-3781 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-92344DOI: 10.1021/la047316vPubMedID: 15835936OAI: oai:DiVA.org:uu-92344DiVA: diva2:165384
Available from: 2004-10-29 Created: 2004-10-29 Last updated: 2017-12-14Bibliographically approved
In thesis
1. On the Structure and Dynamics of Polyelectrolyte Gel Systems and Gel-surfactant Complexes
Open this publication in new window or tab >>On the Structure and Dynamics of Polyelectrolyte Gel Systems and Gel-surfactant Complexes
2004 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

This thesis describes the results of experimental work on polyelectrolyte gels and their interaction with oppositely charged surfactants, and presents two new algorithms applicable to the simulation of colloid and polymer systems.

The model systems investigated were crosslinked poly(acrylate) (PA) and poly(styrene sulphonate) (PSS), and the surfactant was dodecyl trimethylammonium bromide (DoTAB).

Pure gel materials were studied using dynamic light scattering. It was shown that the diffusion coefficient (D) increases with increasing degree of swelling and the concentration dependence is larger than predicted by scaling arguments. For gels at swelling equilibrium D increases with increasing degree of crosslinking.

In subsequent studies on gel particles in DoTAB solution, Raman spectra were recorded at different positions in the gel. For both types of gels two distinct regions could be observed. For PA the surfactant is localised in the outer phase without any surfactant in the core, while for PSS the surfactant was distributed such that it had the same concentration relative to the polymer throughout the gel.

In a second experiment, the kinetics for the deswelling of microscopic PSS particles in DoTAB solution was studied. It was found that the final volume varied linearly with the DoTAB concentration, and the rate of volume decrease could be fitted to a single exponential indicating stagnant layer diffusion to be the rate limiting process for the deswelling of the PSS particles.

In the second part, I first describe an algorithm showing an efficient way to detect percolation in simulations, with periodic boundary conditions, using recursion.

Spherical boundary conditions is an alternative to periodic boundary conditions for systems with long-range interactions. In the last part, the possibility to use the surface of a hypersphere in four dimensions for simulations of polymer systems is investigated, and algorithms for Monte Carlo and Brownian dynamics simulations are described.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2004. 71 p.
Series
Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISSN 1104-232X ; 1036
Keyword
Physical chemistry, polyelectrolyte gel, microgel, dynamic light scattering, Raman spectroscopy, periodic boundary conditions, percolation, hypersphere, Monte Carlo, Brownian dynamics, Fysikalisk kemi
National Category
Physical Chemistry
Identifiers
urn:nbn:se:uu:diva-4652 (URN)91-554-6083-6 (ISBN)
Public defence
2004-11-19, B21, BMC, Husargatan 3, Uppsala, 10:15 (English)
Opponent
Supervisors
Available from: 2004-10-29 Created: 2004-10-29 Last updated: 2013-09-20Bibliographically approved
2. Phase Phenomena in Polymer Networks: Empirical Studies on the Influence of Hydrophobicity, Charge Density and Crosslinks on Macroion-Induced Phase Transitions in Polyelectrolyte Gels
Open this publication in new window or tab >>Phase Phenomena in Polymer Networks: Empirical Studies on the Influence of Hydrophobicity, Charge Density and Crosslinks on Macroion-Induced Phase Transitions in Polyelectrolyte Gels
2011 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

The thesis concerns polyelectrolyte gels in contact with oppositely charged proteins and surfactant micelles, and includes of four papers (I-IV). In paper I confocal Raman spectroscopy was introduced as a method to trace micelles and investigate the structure of gel-surfactant complexes, in phase separated gel spheres. In paper II, the binding of surfactants to microspheres (~50-100 µm) was investigated by means of a micromanipulator-assisted microscopy method. The two surfactants were found to display qualitative difference respect to degree of swelling, surfactant distribution in the gels, and the difference is discussed in terms of absence/presence of hydrophobic attraction to the polyelectrolyte gel network. Kinetics of volume change in gels were analyzed. Aggregation numbers of micelles in polystyrenesulfonate (PSS) solutions, obtained from fluorescence quenching measurements, are presented. In paper III, phase behaviour, protein assembly and diffusion, was studied in PSS gel microspheres. Interpretation of results was aided by measurements of osmotic swelling of individual gel networks, and by combining the results with studies of protein diffusion in macroscopic (cm-sized) gel spheres. Complexes formed were further analyzed with small angle x-ray spectroscopy. In paper IV phase behaviour of mixed ionic/nonionic surfactant micelles is investigated in cm-sized gel spheres. The coexistence of three phases, the formation of dense shells in the bulk of the gels and other phenomena are described for the first time, and the results are presented along with discussion on the charge-density of spherical micelles and of  network induced hysteresis effects in gels. The composition and microstructure of phases are investigated by confocal Raman spectroscopy and small-angle x-ray scattering respectively. The results are interpreted with aid of highly detailed theoretical model calculations.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2011. 53 p.
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy, ISSN 1651-6192 ; 137
Keyword
Gel, microgel, microsphere, polystyrenesulfonate, polyacrylate, polyacrylicacid, DoTAB, DoTAC, CTAB, CTAC, network, polyelectrolyte, complex salt, self assembly, phase behaviour, hysteresis, thermodynamic, core-shell, lysozyme, cytochrome c, microscopy, micromanipulator, elastomer, elastic, protein, surfactant, phase behaviour, sorting
National Category
Pharmaceutical Sciences Physical Chemistry
Identifiers
urn:nbn:se:uu:diva-145381 (URN)978-91-554-8001-1 (ISBN)
Public defence
2011-03-18, B42, BMC, Husargatan 3, Uppsala, 12:30 (Swedish)
Opponent
Supervisors
Available from: 2011-02-24 Created: 2011-02-08 Last updated: 2011-03-11

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Authority records BETA

Elvingson, ChristerHansson, Per

Search in DiVA

By author/editor
Elvingson, ChristerHansson, Per
By organisation
Physical Chemistry IDepartment of Physical ChemistryDepartment of Pharmacy
In the same journal
Langmuir
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 1001 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf