Biochemical indicators of cardiac and renal function in a healthy elderly population
2004 (English)In: Clinical Biochemistry, ISSN 0009-9120, E-ISSN 1873-2933, Vol. 37, no 3, 210-216 p.Article in journal (Refereed) Published
To examine the distributions of NT-proBNP and cystatin C and their relation to age, gender, and other physiological factors in an apparently healthy elderly population.
NT-proBNP and cystatin C were analyzed in 407 and 408 healthy individuals, median age: 65 (range 40–76).
Increasing age, female gender and CRP were independently associated to higher NT-proBNP levels. Age, body mass index, and CRP level were independently associated to the cystatin C level. In women and men, ≤65 years, the 97.5th percentile value for NT-proBNP was 268 ng/l and 184 ng/l, in those older, 391 ng/l and 269 ng/l. For those ≤65 years the 97.5th percentile value for cystatin C was 1.12 mg/l, and for those older 1.21 mg/l.
In a healthy elderly population, NT-proBNP is influenced by age and gender, whereas cystatin C is influenced by age but not by gender. Both markers seem to be associated to the CRP level.
Place, publisher, year, edition, pages
2004. Vol. 37, no 3, 210-216 p.
NT-proBNP, Cystatin C, Cardiac and renal function, Healthy elderly population
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-94119DOI: 10.1016/j.clinbiochem.2003.11.002PubMedID: 14972643OAI: oai:DiVA.org:uu-94119DiVA: diva2:167864