Molecular dynamics of a biodegradable biomimetic ionomer studied by broadband dielectric spectroscopy
2007 (English)In: Langmuir, ISSN 0743-7463, E-ISSN 1520-5827, Vol. 23, no 20, 10209-10215 p.Article in journal (Refereed) Published
Broadband dielectric spectroscopy was used to investigate the bulk molecular dynamics of a recently developed biodegradable biomimetic ionomer potentially useful for biomedical applications. Isothermal dielectric spectra were gathered for a phosphoryl choline (PC)-functionalized poly(trimethylene carbonate) (PTMC) ionomer and unfunctionalized PTMC at temperatures ranging from 2 to 60 degrees C over a broad frequency range of 10(-3) to 10(6) Hz. Four relaxations were clearly identified, two of which were shown to stem from the PTMC polymer backbone. A detailed analysis showed that the formation of zwitterionic aggregates was responsible for the material's bulk functionality and that bulk conduction processes may provide useful information for assessing the PC ionomer as a candidate for drug delivery applications. Finally, it was concludedthat absorbed water concentrates around the aggregates, resulting in an increased mobility of the PC end-groups.
Place, publisher, year, edition, pages
2007. Vol. 23, no 20, 10209-10215 p.
Natural Sciences Engineering and Technology
Research subject Engineering Science with specialization in Nanotechnology and Functional Materials
IdentifiersURN: urn:nbn:se:uu:diva-94619DOI: 10.1021/la7009012ISI: 000249560100039OAI: oai:DiVA.org:uu-94619DiVA: diva2:168524