Differences in adherence and motivation to HIV therapy: Two independent assessments in 1998 and 2002
2006 (English)In: Pharmacy World & Science, ISSN 0928-1231, E-ISSN 1573-739X, Vol. 28, no 4, 248-256 p.Article in journal (Refereed) Published
Objective: The aim of this study was to compare the level of adherence and motivation in two independent cross-sectional samples of HIV-infected patients conducted in 1998 and 2002, and to investigate the relationship between adherence and motivation. Method: Consecutive HIV-infected patients on treatment at a Swedish clinic were asked to complete an anonymous questionnaire. In 1998, 60 patients participated and in 2002, 53 participated. In 2002, the 9-item Morisky Medication Adherence Scale (MMAS) was added to the questionnaire set. Main outcome measure: Self-reported adherence and motivation. Results: In 1998, 28.1% of the respondents were considered adherent, while the corresponding proportion was 57.4% in 2002 (P = 0.002). The mean summary score for MMAS was 10.7 in 2002 (13 = perfect adherence). The proportion considered motivated were 22.4% in the 1998 survey and 41.3% in 2002 (P = 0.038). Of the respondents considered motivated in the 2002 survey, 46.7% scored the maximum summary score on the MMAS, while 8.7% of the non-motivated respondents did so (P = 0.016). Conclusion: The respondents in 2002 were more adherent and motivated than the respondents in 1998 and a relationship between motivation and adherence was found. The difference in adherence and motivation might be due to a new treatment model at the clinic.
Place, publisher, year, edition, pages
2006. Vol. 28, no 4, 248-256 p.
Acquired immunodeficiency syndrome, AIDS, Highly active antiretroviral therapy, HIV, MMAS, Patient adherence, Patient compliance, Patient motivation, Pharmacotherapy, Sweden
IdentifiersURN: urn:nbn:se:uu:diva-95138DOI: 10.1007/s11096-006-9036-4ISI: 000241727000010PubMedID: 17066240OAI: oai:DiVA.org:uu-95138DiVA: diva2:169233