Cholinergic neuromuscular hyperactivity in patients with myasthenia gravis seropositive for MuSK antibody
2006 (English)In: Muscle and Nerve, ISSN 0148-639X, E-ISSN 1097-4598, Vol. 34, no 1, 111-115 p.Article in journal (Refereed) Published
A 75-year-old man with severe oculobulbar myasthenia gravis (MG) treated with acetylcholine esterase inhibitors (AChEIs) was found to have muscle-specific tyrosine kinase (MuSK) antibodies. Neurophysiological examination displayed extra repetitive discharges after the compound motor action potential (CMAP) at low-frequency stimulation, possibly triggered by AChEI. This indicates an abnormal sensitivity to acetylcholine in patients with MuSK antibodies and may be a useful indicator of the adverse effect of AChEI treatment in these patients. Muscle Nerve, 2006
Place, publisher, year, edition, pages
2006. Vol. 34, no 1, 111-115 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-95261DOI: 10.1002/mus.20515PubMedID: 16453324OAI: oai:DiVA.org:uu-95261DiVA: diva2:169409