Complementary sequence preferences of electron-capture dissociation and vibrational excitation in fragmentation of polypeptide polycations
2006 (English)In: Angewandte Chemie International Edition, ISSN 1433-7851, E-ISSN 1521-3773, Vol. 45, no 32, 5301-5303 p.Article in journal (Refereed) Published
(Chemical Equation Presented) Complementary cleavage: A large-scale (ca. 15000 spectra) comparison between the cleavage sites and the preferences of collision-activated dissociation (CAD) and electron-capture dissociation (ECD) in tandem mass spectrometry has proved beyond doubt their complementary nature (see picture, red: high, blue: low). The study has also suggested the presence of a preferred N-terminal structure in gas-phase tryptic peptide dications.
Place, publisher, year, edition, pages
2006. Vol. 45, no 32, 5301-5303 p.
collision-activated dissociation, electron-capture dissociation, ion-electron reactions, mass spectrometry, peptide fragmentation
Engineering and Technology
IdentifiersURN: urn:nbn:se:uu:diva-95356DOI: 10.1002/anie.200601240ISI: 000239913400010PubMedID: 16847865OAI: oai:DiVA.org:uu-95356DiVA: diva2:169533