Building blood vessels- Stem cell models in vascular biology
2007 (English)In: Journal of Cell Biology, ISSN 0021-9525, E-ISSN 1540-8140, Vol. 177, no 5, 751-755 p.Article, review/survey (Refereed) Published
Spheroids of differentiating embryonic stem cells, denoted embryoid bodies, constitute a high-quality model for vascular development, particularly well suited for loss-of-function analysis of genes required for early embryogenesis. This review examines vasculogenesis and angiogenesis in murine embryoid bodies and discusses the promise of stem cell–based models for the study of human vascular development.
Place, publisher, year, edition, pages
2007. Vol. 177, no 5, 751-755 p.
Animals, Cell Differentiation, Embryonic Stem Cells/*cytology, Humans, Mice, Mice; Transgenic, Neovascularization; Physiologic/genetics/*physiology
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-95544DOI: 10.1083/jcb.200701146ISI: 000247072700002PubMedID: 17535968OAI: oai:DiVA.org:uu-95544DiVA: diva2:169804