Factors associated with adherence to drug therapy: a population-based study
2007 (English)In: European Journal of Clinical Pharmacology, ISSN 0031-6970, E-ISSN 1432-1041, Vol. 63, no 3, 307-314 p.Article in journal (Refereed) Published
Objective To investigate adherence to prescription in a female population aged 35–65 years.
Design Postal questionnaire study of 2991 randomly sampled 35- to 64-year-old women in seven provinces of central Sweden. Methods The study was performed in 1995 as a cross-sectional postal questionnaire study in seven counties in central Sweden. The questionnaire was sent to a random sample of 4200 women between the ages of 35 and 64, of whom 2991 (71.2%) responded. The questionnaire asked about drugs prescribed during the past year and about factors potentially affecting adherence. Results The same women had different degrees of adherence to different medications. A large number of factors were associated with adherence. Multivariate analysis revealed that age, scheduled check-up, perceived importance of medication, concerns about medication safety and taking medication for a respiratory or a cardiovascular disease were significantly related to adherence. Adherence ranged from 15–98% depending on these factors, and was the lowest among young women who regarded their medication as unimportant and who had no scheduled check-up; the highest reported adherence was found among elderly women who regarded their medication as important and who had a scheduled check-up. Conclusion Factors that were associated with the perceived importance of medication had a positive effect on adherence, while concerns about medication safety had a negative effect.
Place, publisher, year, edition, pages
2007. Vol. 63, no 3, 307-314 p.
Adherence, Communication skills, Epidemiology, Prescription, Women
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-96255DOI: 10.1007/s00228-006-0246-4ISI: 000244091900012PubMedID: 17211620OAI: oai:DiVA.org:uu-96255DiVA: diva2:170766