The 4C technique: the ‘Rosetta stone’ for genome biology in 3D?
2007 (English)In: Current Opinion in Cell Biology, ISSN 0955-0674, E-ISSN 1879-0410, Vol. 19, no 3, 321-325 p.Article in journal (Refereed) Published
Despite considerable efforts, the spatial link between the nuclear architecture and the genome remains enigmatic. The 4C method, independently innovated in four different laboratories, might in combination with other methods change that. As this method is based on the unbiased identification of sequences interacting with specific baits, there are unique opportunities for unravelling the secrets of how the genome functions in 3D.
Place, publisher, year, edition, pages
2007. Vol. 19, no 3, 321-325 p.
IdentifiersURN: urn:nbn:se:uu:diva-96392DOI: 10.1016/j.ceb.2007.04.008ISI: 000247775200012OAI: oai:DiVA.org:uu-96392DiVA: diva2:170951