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Hardware accelerated visualization of parametrically mapped dynamic breast MRI data
Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science, Centre for Image Analysis.
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2007 (English)In: Proceedings of MICCAI workshop: Interaction in Medical Image Analysis and Visualization, 2007, 33-40 p.Conference paper (Refereed)
Abstract [en]

We present a new approach to visualising parametric vol-umes obtained in voxel-wise model fitting of dynamic contrast-enhanced(DCE) MRI data of the breast. The visualisation makes use of hardware-accelerated rendering to obtain an interactive, 3D colour-correct maxi-mum intensity projection (MIP). The method has been realised in soft-ware that permits the user to not only interactively visualise the paramet-ric volume but also to delineate 3D regions of interest using a 2D slice-wise interface. Experimental results, based on 14 DCE-MRI data setsfrom routine clinical practice, show that using the visualisation/tracingtool a medically qualified operator can achieve the same sensitivity forthe detection of malignancy as a radiologist using conventional manualinterpretation, but with better specificity. The results demonstrate thatthe visualisation methodology/software has potential as a tool for assist-ing the radiologist with the task of interpreting 4D DCE-MRI data inthe routine clinical setting.

Place, publisher, year, edition, pages
2007. 33-40 p.
National Category
Computer and Information Science
URN: urn:nbn:se:uu:diva-96644ISBN: 978 0 643 09521 2OAI: oai:DiVA.org:uu-96644DiVA: diva2:171285
MICCAI 2007: The 10th International Conference on Medical Image Computing and Computer Assisted Intervention
Available from: 2008-01-18 Created: 2008-01-18 Last updated: 2010-05-17Bibliographically approved
In thesis
1. Visualization and Haptics for Interactive Medical Image Analysis
Open this publication in new window or tab >>Visualization and Haptics for Interactive Medical Image Analysis
2008 (English)Doctoral thesis, comprehensive summary (Other academic)
Alternative title[sv]
Visualisering och Haptik för Interaktiv Medicinsk Bildanalys
Abstract [en]

Modern medical imaging techniques provide an increasing amount of high-dimensional and high-resolution image data that need to be visualized, analyzed, and interpreted for diagnostic and treatment planning purposes. As a consequence, efficient ways of exploring these images are needed. In order to work with specific patient cases, it is necessary to be able to work directly with the medical image volumes and to generate the relevant 3D structures directly as they are needed for visualization and analysis. This requires efficient tools for segmentation, i.e., separation of objects from each other and from the background. Segmentation is hard to automate due to, e.g., high shape variability of organs and limited contrast between tissues. Manual segmentation, on the other hand, is tedious and error-prone. An approach combining the merits from automatic and manual methods is semi-automatic segmentation, where the user interactively provides input to the methods. For complex medical image volumes, the interactive part can be highly 3D oriented and is therefore dependent on the user interface.

This thesis presents methods for interactive segmentation and visualization where true 3D interaction with haptic feedback and stereo graphics is used. Well-known segmentation methods such as fast marching, fuzzy connectedness, live-wire, and deformable models, have been tailored and extended for implementation in a 3D environment where volume visualization and haptics are used to guide the user. The visualization is accelerated with graphics hardware and therefore allows for volume rendering in stereo at interactive rates. The haptic feedback is rendered with constraint-based direct volume haptics in order to convey information about the data that is hard to visualize and thereby facilitate the interaction. The methods have been applied to real medical images, e.g., 3D liver CT data and 4D breast MR data with good results. To provide a tool for future work in this area, a software toolkit containing the implementations of the developed methods has been made publicly available.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2008. 83 p.
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISSN 1651-6214 ; 386
Bildanalys, medical image analysis, haptic rendering, volume visualization, interactive segmentation, Bildanalys
urn:nbn:se:uu:diva-8409 (URN)978-91-554-7067-8 (ISBN)
Public defence
2008-02-08, Häggsalen, Ångströmlaboratoriet, Polacksbacken, Uppsala, 10:15 (English)
Available from: 2008-01-18 Created: 2008-01-18 Last updated: 2010-05-12Bibliographically approved

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