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Impaired insulin sensitivity is an independent predictor of common carotid intima-media thickness in a population sample of elderly men.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Public Health and Caring Sciences.
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2003 In: Atherosclerosis, Vol. 170, no 1, 181-185 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2003. Vol. 170, no 1, 181-185 p.
Identifiers
URN: urn:nbn:se:uu:diva-97037OAI: oai:DiVA.org:uu-97037DiVA: diva2:171814
Available from: 2008-04-25 Created: 2008-04-25Bibliographically approved
In thesis
1. Carotid Vessel Wall Thickness and Echogenicity: In the ULSAM study
Open this publication in new window or tab >>Carotid Vessel Wall Thickness and Echogenicity: In the ULSAM study
2008 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

In this thesis the common carotid artery intima media thickness in nearly 500 elderly men is independently associated with insulin sensitivity, measured by the gold standard hyperinsulinemic euglycemic clamp test (paper 1), to both COX- and cytokine mediated inflammation independently of other markers of inflammation, oxidative stress and antioxidant status (paper 2) and also to the alleles of the apolipoprotein gene independently of lipid levels and cardiovascular risk factors (paper 3). The echogenicity of the carotid intima-media complex measured as grey scale median predicts mortality independently of common carotid artery intima-media thickness, prior cardiovascular disease and cardiovascular risk factors (paper 4).

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2008. 106 p.
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 1651-6206 ; 332
Keyword
Medicine, Epidemiology, Medicin
Identifiers
urn:nbn:se:uu:diva-8642 (URN)978-91-554-7161-3 (ISBN)
Public defence
2008-05-09, Robergsalen, ingång 40 plan 4, Akademiska sjukhuset, Uppsala, 13:15 (English)
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Available from: 2008-04-25 Created: 2008-04-25 Last updated: 2009-10-06Bibliographically approved

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