Tooth loss is related to the presence of the metabolic syndrome and inflammation in elderly subjects: A prospective study of the vasculature in Uppsala seniors (PIVUS)
2007 (English)In: Oral Health & Preventive Dentistry, ISSN 1602-1622, Vol. 5, no 2, 125-130 p.Article in journal (Refereed) Published
PURPOSE: To investigate how the number of remaining teeth relates to the presence of metabolic syndrome (MetS) and markers of inflammation. MATERIALS AND METHODS: A population-based prospective investigation of the vasculature in Uppsala seniors (PIVUS) study was carried out on 1016 subjects, aged 70. RESULTS: The number of teeth was self-reported in 947 subjects and was found to be less in those with MetS using National Cholesterol Education Program/Adult Treatment Panel III (NCEP/ATP Ill) criteria (n = 219, mean 17.7 +/- 9.0 [SD]), compared with n = 728, mean 20.7 +/- 7.2 in those without MetS (p < 0.0001), and in proportion to the number of criteria fulfilled (p < 0.0001). The number of teeth was also inversely related to markers of inflammation (r = -0.15, p < 0.0001 for leukocyte count; r = -0.10, p = 0.0023 for C-reactive protein). In a multiple regression analysis, the presence of MetS, smoking, educational level, leukocyte count and height were independent predictors of the number of teeth. CONCLUSIONS: In addition to established risk factors for tooth loss, the presence of MetS and inflammation were independent predictors of the number of teeth in an elderly population.
Place, publisher, year, edition, pages
2007. Vol. 5, no 2, 125-130 p.
C-reactive protein (CRP), inflammation, metabolic syndrome, oral health, teeth
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-97156OAI: oai:DiVA.org:uu-97156DiVA: diva2:171972