High Stereoselectivity in Chelation-Controlled Intermolecular Heck Reactions with Aryl Chlorides, Vinyl Chlorides and Vinyl Triflates
2008 (English)In: Organic and biomolecular chemistry, ISSN 1477-0520, E-ISSN 1477-0539, Vol. 6, no 4, 674-676 p.Article in journal (Refereed) Published
Highly stereoselective chelation-controlled Pd(0)-catalyzed beta-arylations and beta-vinylations of a five-membered chiral, pyrrolidine-based vinyl ether were achieved using aryl- and vinyl chlorides as substrates, yielding quaternary 2-aryl/vinyl-2-methyl cyclopentanones in 89-96% ee under neutral reaction conditions.
Place, publisher, year, edition, pages
2008. Vol. 6, no 4, 674-676 p.
IdentifiersURN: urn:nbn:se:uu:diva-97434DOI: 10.1039/b719131fISI: 000253014900005PubMedID: 18264566OAI: oai:DiVA.org:uu-97434DiVA: diva2:172384