In this chapter we will highlight and broaden the concept of Quantum Darwinism to incorporate an extension to thermodynamic open systems. The strategy will be a bit different compared to the conventional approach in that the formulation, rather than offering a fundamental discussion of the classical measurement problem, derives a more general steady-state picture, where ultimately the dissipative organization of the quantum system is properly thermalized and spatio-temporally tuned from first principles. Two cases will be discussed: (i) the human brain and (ii) the black hole. Both are treated as open non-equilibrium systems, where the brain, conjugate to the mind, exhibits negentropic gain, and a thermo-qubit syntax for communication. The second example, a quantum analogue of a black hole, is demonstrated to exhibit Hawking radiation including the explicit connection between the black hole surface area and the entropy. The results are derived from the axiomatic structure of pioneering quantum chemistry with rigorous extensions to open system adaptation in the Schrödinger-Liouville-Bloch formalism at steady state conditions. The approach suggests a prolegomenon for Hilbert's sixth problem.