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A follow up of adolescents and young adults with asthma:  airway hyperresponsiveness and asthma control.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm , Centrum för klinisk forskning i D län (CKFD).
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Family Medicine and Clinical Epidemiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Family Medicine and Clinical Epidemiology.
(English)Article in journal (Refereed) Submitted
Identifiers
URN: urn:nbn:se:uu:diva-97667OAI: oai:DiVA.org:uu-97667DiVA: diva2:172695
Available from: 2008-10-30 Created: 2008-10-30 Last updated: 2012-01-09Bibliographically approved
In thesis
1. Asthma in Primary Care: Severity, Treatment and Level of Control
Open this publication in new window or tab >>Asthma in Primary Care: Severity, Treatment and Level of Control
2008 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Aims. The overall aim was to examine the severity, treatment and level of control in patients with asthma in primary care in Sweden. The specific aims were to assess what matters to asthma patients, evaluate symptoms, medication and identify factors related to asthma severity, compare the extent of asthma control in 2001 and 2005, and investigate the development of asthma and degree of asthma control in adolescents and young adults who had reported asthma six years earlier.

Methods. The first study was a telephone interview of a representative sample of Swedish asthmatics. In the second study a random sample of 1,136 patients answered two questionnaires. A classification of the asthma severity similar to that in the GINA guidelines was made. In the third study two surveys were performed, in 2001 and in 2005, with a random sample of 1,012 and 224 asthma patients, respectively, and a classification of asthma control similar to the recent GINA guidelines was made. In the fourth study 71 individuals who reported physician-diagnosed asthma in a population-based survey in 1997 and were defined as current asthmatics, were reinvestigated in 2003 with a skin prick test, methacholine challenge test, eucapnic voluntary hyperventilation test and measurement of exhaled nitric oxide.

Results. Common situations causing symptoms of asthma were physical exertion and contact with pets. Nocturnal symptoms were frequent. In primary care 35% of the women and 24% of the men were classified as having severe asthma. Female sex, increasing age, not filling the asthma prescription owing to cost, daily smoking, and pollen allergy increased the odds of having severe asthma. In 2001, 37% had achieved asthma control, as compared with 40% in 2005. Uncontrolled asthma was more common in women and smokers. In the 2003 study of adolescents and young adults with asthma six years earlier, the definition of current asthma was fulfilled by 50 of the 71 subjects and one third had achieved asthma control.

Conclusions. The majority of the asthmatics reported a large number of symptoms and limitations in their daily living. Many asthma patients in primary care have insufficient asthma control. One reason for lack of control might be undertreatment with inhaled corticosteroids.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2008. 76 p.
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 1651-6206 ; 390
Keyword
Adherence, adolescent, adult, asthma, asthma classification, asthma control, asthma severity, compliance, drug therapy, hyperresponsiveness, primary health care, smoking, asthma treatment.
National Category
Family Medicine
Identifiers
urn:nbn:se:uu:diva-9332 (URN)978-91-554-7315-0 (ISBN)
Public defence
2008-11-21, Rudbeckssalen, Rudbecklaboratoriet, Dag Hammarskölds väg 20, Uppsala, 13:15 (English)
Opponent
Supervisors
Available from: 2008-10-30 Created: 2008-10-30 Last updated: 2011-05-13Bibliographically approved

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Ställberg, BjörnJohansson, GunnarSvärdsudd, Kurt

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Department of Public Health and Caring SciencesCentrum för klinisk forskning i D län (CKFD)Family Medicine and Clinical Epidemiology

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CiteExportLink to record
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