Dietary supplementation with casein/cyanidin-3-O-glucoside nanoparticles alters the gut microbiota in high-fat fed C57BL/6 miceShow others and affiliations
2023 (English)In: Food Chemistry, ISSN 0308-8146, E-ISSN 1873-7072, Vol. 412, article id 135494Article in journal (Refereed) Published
Abstract [en]
This study aims to investigate the dietary intervention effect of casein/cyanidin-3-O-glucoside nanoparticles (CsC3G) on high-fat-diet (HFD)induced gut microbiota disorders. In HFD-fed C57BL/6mice, Cs-C3G has ameliorated HFD-caused fat accumulation and liver oxidative stress. Cs-C3G as a dietary supplementation can restore the abundance and diversity of gut microbiota with descending the ratio of Firmicutes to Bacteroidetes, increasing some beneficial microorganisms, and reducing some opportunistic pathogenic bacteria. In general, Cs-C3G has a effect on regulating the disturbance of gut microbiota, and then prevents HFD-induced obesity and liver damage.
Place, publisher, year, edition, pages
ELSEVIER SCI LTD Elsevier, 2023. Vol. 412, article id 135494
Keywords [en]
Cyanidin-3-O-glucoside, Nanoparticles, High -fat -diet, Gut microbiota
National Category
Food Science
Identifiers
URN: urn:nbn:se:uu:diva-501161DOI: 10.1016/j.foodchem.2023.135494ISI: 000963681900001PubMedID: 36736183OAI: oai:DiVA.org:uu-501161DiVA, id: diva2:1755016
2023-05-052023-05-052024-01-15Bibliographically approved