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Outcomes of aortic arch repair using the frozen elephant trunk technique: analysis of a Scandinavian center's results over 14 years
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery. Uppsala Univ, Dept Surg Sci, Sect Vasc Surg, Uppsala, Sweden..
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery. Uppsala Univ, Dept Surg Sci, Sect Vasc Surg, Uppsala, Sweden..ORCID iD: 0000-0002-3273-8726
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Disciplinary Domain of Medicine and Pharmacy, research centers etc., Centre for Clinical Research, County of Västmanland. Uppsala Univ, Dept Surg Sci, Sect Cardiothorac Surg, Uppsala, Sweden..
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Thoracic Surgery. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Anaesthesiology and Intensive Care. Uppsala Univ, Dept Surg Sci, Sect Cardiothorac Surg, Uppsala, Sweden..ORCID iD: 0000-0001-8825-896X
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2023 (English)In: Journal of Cardiovascular Surgery, ISSN 0021-9509, E-ISSN 1827-191X, Vol. 64, no 2, p. 215-223Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: The frozen elephant trunk (FET) technique enables repair of aortic arch pathology, with possibility for endovascular treat-ment of distal thoracic aortic disease. We aimed to study outcomes of FET repair of complex aortic arch disease at a Scandinavian tertiary referral center. METHODS: All patients who underwent FET repair of the aortic arch 2006-2020 were included. Survival, complication and reintervention rate, and aortic remodeling were analyzed. RESULTS: Fifty patients were included: 23 complex thoracic aortic aneurysms involving the aortic arch (TAA), 19 with chronic aortic dis-sections (CAD) (16 Stanford type A, 3 type B) and 8 acute aortic dissections (AAD) (7 Stanford type A, 1 type B). Thirty-day mortality was: TAA=22% (N.=5), CAD=5% (N.=1), AAD=37% (N.=3). Rate of disabling stroke: TAA=22% (N.=5), CAD=5% (N.=1), AAD=25% (N.=2). Rate of permanent spinal cord injury: TAA=9% (N.=2), CAD=5% (N.=1), AAD=0%. 5-year survival: TAA=53%, CAD=83%, AAD=63%. 5-year reintervention-free survival was TAA=83% and CAD=36%. There were no reinterventions in the AAD group. 13/19 (68%) of CAD patients underwent distal stent graft extension during follow-up. On last CT follow-up (median 32 months), 78% of CAD had false lumen thrombosis along the stent graft and 11% in the abdominal aorta. In thoracic aorta there was a mean 64% expansion (P<0.001) of true and 39% reduction (P=0.007) of false lumen diameter. In abdominal aorta, both true and false lumen expanded. CONCLUSIONS: Despite the advantages of the FET technique, repair of extensive aortic arch disease remains associated with high rates of mortality and major neurologic complications. FET repair of CAD induces favorable remodeling in the thoracic aorta.

Place, publisher, year, edition, pages
EDIZIONI MINERVA MEDICA , 2023. Vol. 64, no 2, p. 215-223
Keywords [en]
Endovascular aneurysm repair, Aortic aneurysm, thoracic, Aortic dissection
National Category
Cardiology and Cardiovascular Disease Surgery
Identifiers
URN: urn:nbn:se:uu:diva-502106DOI: 10.23736/S0021-9509.23.12490-6ISI: 000969195900011PubMedID: 36987817OAI: oai:DiVA.org:uu-502106DiVA, id: diva2:1776871
Available from: 2023-06-28 Created: 2023-06-28 Last updated: 2025-02-10Bibliographically approved

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Hellgren, TinaWanhainen, AndersVikholm, PerHellgren, LailaMani, Kevin

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Vascular SurgeryCentre for Clinical Research, County of VästmanlandThoracic SurgeryAnaesthesiology and Intensive Care
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