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Evidence and research in rectal cancer
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2008 (English)In: Radiotherapy and Oncology, ISSN 0167-8140, E-ISSN 1879-0887, Vol. 87, no 3, 449-474 p.Article, review/survey (Refereed) Published
Abstract [en]

The main evidences of epidemiology, diagnostic imaging, pathology, surgery, radiotherapy, chemotherapy and follow-up are reviewed to optimize the routine treatment of rectal cancer according to a multidisciplinary approach. This paper reports on the knowledge shared between different specialists involved in the design and management of the multidisciplinary ESTRO Teaching Course on Rectal Cancer. The scenario of ongoing research is also addressed. In this time of changing treatments, it clearly appears that a common standard for large heterogeneous patient groups have to be substituted by more individualised therapies based on clinical-pathological features and very soon on molecular and genetic markers. Only trained multidisciplinary teams can face this new challenge and tailor the treatments according to the best scientific evidence for each patient.

Place, publisher, year, edition, pages
2008. Vol. 87, no 3, 449-474 p.
Keyword [en]
rectal cancer treatment, epidemiology, diagnostic, endorectal ultrasound, computerized tomography, magnetic resonance imaging, pathology, surgery, total mesorectal excision, local excision, combined modality therapy, radiotherapy, pre-operative treatment, post-operative treatment, radiotherapy technique, chemotherapy, concomitant radiochemotherapy, adjuvant chemotherapy, early stage, intermediate stage, advanced stage, local recurrence, acute and late toxicity, quality of life, follow-up, scenario of ongoing research, educational, randomized clinical trial, intraoperative radiotherapy
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-98967DOI: 10.1016/j.radonc.2008.05.022ISI: 000257631700023PubMedID: 18534701OAI: oai:DiVA.org:uu-98967DiVA: diva2:201741
Available from: 2009-03-05 Created: 2009-03-05 Last updated: 2011-01-13Bibliographically approved

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