Iridium Catalysts with Chiral Imidazole-Phosphine Ligands for Asymmetric Hydrogenation of Vinyl Fluorides and other Olefins
2008 (English)In: Advanced Synthesis and Catalysis, ISSN 1615-4150, E-ISSN 1615-4169, Vol. 350, no 7-8, 1168-1176 p.Article in journal (Refereed) Published
New chiral bidentate imidazole-phosphine ligands have been prepared and evaluated for the iridium-catalysed asymmetric hydrogenation of olefins. The imidazole-phosphine-ligated iridium catalysts hydrogenated trisubstituted olefins with the same sense of enantiodiscrimination as known iridium catalysts possessing oxazole and thiazole as N-donors. The imidazole-based catalysts were shown to hydrogenate vinyl fluorides, in some cases with the highest ee values published to date.
Place, publisher, year, edition, pages
2008. Vol. 350, no 7-8, 1168-1176 p.
asymmetric hydrogenation, iridium, N, P donating ligand, vinyl fluorides
Analytical Chemistry Organic Chemistry
IdentifiersURN: urn:nbn:se:uu:diva-99805DOI: 10.1002/adsc.200800062OAI: oai:DiVA.org:uu-99805DiVA: diva2:208776