Cascade synthesis with (triphenylphosphoranylidene)ethenone as a versatile reagent for fast synthesis of heterocycles and unsaturated amides under microwave dielectric heating
2002 (English)In: Combinatorial chemistry & high throughput screening, ISSN 1386-2073, Vol. 5, no 7, 571-574 p.Article in journal (Refereed) Published
A general procedure for the synthesis of a large variety of compounds comprising an alpha, beta-unsaturated carbonyl functionality was developed. The use of one-pot cascade synthesis with (triphenylphosphoranylidene)ethenone as a versatile reagent for various formations including heterocycles of different ring sizes and unsaturated amides in combination with microwave dielectric heating is described. The method was used to synthesize a small library of unsaturated amides.
Place, publisher, year, edition, pages
2002. Vol. 5, no 7, 571-574 p.
microwave heating, one-pot synthesis, cascade reaction, library synthesis, (triphenylphosphoranylidene)ethenone, organic-synthesis, cumulated ylides, chemistry
IdentifiersURN: urn:nbn:se:uu:diva-100964ISI: 000181710400008PubMedID: 12470270ISBN: 1386-2073OAI: oai:DiVA.org:uu-100964DiVA: diva2:211425