uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Structure and function of Rubisco
Department of Molecular Biology, Swedish University of Agricultural Sciences.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Medicinal Chemistry, Division of Pharmacognosy.
2008 (English)In: Plant physiology and biochemistry (Paris), ISSN 0981-9428, E-ISSN 1873-2690, Vol. 46, no 3, 275-291 p.Article in journal (Refereed) Published
Abstract [en]

Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) is the major enzyme assimilating CO2 into the biosphere. At the same time Rubisco is an extremely inefficient catalyst and its carboxylase activity is compromised by an opposing oxygenase activity involving atmospheric O2. The shortcomings of Rubisco have implications for crop yield, nitrogen and water usage, and for the global carbon cycle. Numerous high-resolution crystal structures of different forms of Rubisco are now available, including structures of mutant enzymes. This review uses the information provided in these structures in a structure-based sequence alignment and discusses Rubisco function in the context of structural variations at all levels – amino acid sequence, fold, tertiary and quaternary structure – with an evolutionary perspective and an emphasis on the structural features of the enzyme that may determine its function as a carboxylase.

Place, publisher, year, edition, pages
2008. Vol. 46, no 3, 275-291 p.
National Category
Biochemistry and Molecular Biology
URN: urn:nbn:se:uu:diva-102012DOI: 10.1016/j.plaphy.2008.01.001ISI: 000255378400005PubMedID: 18294858OAI: oai:DiVA.org:uu-102012DiVA: diva2:213859
Available from: 2009-04-29 Created: 2009-04-29 Last updated: 2016-05-10

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Andersson, IngerBacklund, Anders
By organisation
Division of Pharmacognosy
In the same journal
Plant physiology and biochemistry (Paris)
Biochemistry and Molecular Biology

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 221 hits
ReferencesLink to record
Permanent link

Direct link