uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Autoimmune and inflammatory disorders and risk of malignant lymphomas: an update
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Rheumatology.
2008 (English)In: Journal of Internal Medicine, ISSN 0954-6820, E-ISSN 1365-2796, Vol. 264, no 6, 514-527 p.Article, review/survey (Refereed) Published
Abstract [en]

As specific autoimmune disorders now constitute established risk factors for malignant lymphomas, we describe this association.

We review reported risk levels, risk determinants, lymphoma subtypes and biological mechanisms in autoimmunity/inflammation, emphasizing on recent findings.

Whilst numerous reports describe average lymphoma risks in large patient groups, there's a recent shift of focus to risk determinants and the role of inflammatory activity. Studies highlight associations with diffuse large B-cell lymphoma, apart from lymphoma development in target organs of inflammation.

Future studies of high-risk patient subsets using detailed assessments of autoimmunity/inflammation and lymphoma may give important clues to lymphomagenesis.

Place, publisher, year, edition, pages
2008. Vol. 264, no 6, 514-527 p.
Keyword [en]
Autoimmunity, Chronic inflammation, Immune stimulation, Malignant lymphoma
National Category
Clinical Medicine
URN: urn:nbn:se:uu:diva-102204DOI: 10.1111/j.1365-2796.2008.02029.xISI: 000260823800003PubMedID: 19017176OAI: oai:DiVA.org:uu-102204DiVA: diva2:214514
Available from: 2009-05-05 Created: 2009-05-05 Last updated: 2015-03-11Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Baecklund, Eva
By organisation
In the same journal
Journal of Internal Medicine
Clinical Medicine

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 200 hits
ReferencesLink to record
Permanent link

Direct link