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Prediction of ADMET Properties
AstraZeneca R&D Södertälje.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacy. (Drug delivery)
2006 (English)In: ChemMedChem, Vol. 1, no 9, 920-937 p.Article, review/survey (Refereed) Published
Abstract [en]

This Review describes some of the approaches and techniques used today to derive in silico models for the prediction of ADMET properties. The article also discusses some of the fundamental requirements for deriving statistically sound and predictive ADMET relationships as well as some of the pitfalls and problems encountered during these investigations. It is the intension of the authors to make the reader aware of some of the challenges involved in deriving useful in silico ADMET models for drug development.

Place, publisher, year, edition, pages
Wiley-VCH , 2006. Vol. 1, no 9, 920-937 p.
National Category
Pharmaceutical Sciences
URN: urn:nbn:se:uu:diva-102253DOI: 10.1002/cmdc.200600155OAI: oai:DiVA.org:uu-102253DiVA: diva2:214555
Available from: 2009-05-06 Created: 2009-05-06 Last updated: 2010-07-20Bibliographically approved

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Bergström, Christel
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