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Prostasomer och exosomer - cellbudbärare med terapeutisk potentia
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Chemistry. (biologisk struktur och funktion)
2007 (Swedish)In: Läkartidningen, ISSN 0023-7205, Vol. 104, no 10, 784-786 p.Article in journal (Refereed) Published
Abstract [en]

Prostasomes and exosomes are kindred natures. They are small organellar structures harboured in multivesicular bodies (”storage vesicles”) and released by exocytosis into the extracellular space. They are surrounded by a complex bilayered, sometimes multilayered, membrane. The pluripotency of prostasomes favours the normal reproductive process in different ways and later on in life they may be involved in the propagation of prostate cancer.Exosomes can function in a multitude of processes, e.g. intercellular communication during immune response and they can indirectly stimulate the immune system. They are being used in clinical trials as tumour antigen bearers to trigger tumour rejection by the body.

Place, publisher, year, edition, pages
2007. Vol. 104, no 10, 784-786 p.
Keyword [sv]
Exocytos, Sekretoriska blåsor, Cellkommunikation
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-102289PubMedID: 17432796OAI: oai:DiVA.org:uu-102289DiVA: diva2:214591
Available from: 2009-05-06 Created: 2009-05-06 Last updated: 2010-04-06Bibliographically approved

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