Prostasomer och exosomer - cellbudbärare med terapeutisk potentia
2007 (Swedish)In: Läkartidningen, ISSN 0023-7205, Vol. 104, no 10, 784-786 p.Article in journal (Refereed) Published
Prostasomes and exosomes are kindred natures. They are small organellar structures harboured in multivesicular bodies (”storage vesicles”) and released by exocytosis into the extracellular space. They are surrounded by a complex bilayered, sometimes multilayered, membrane. The pluripotency of prostasomes favours the normal reproductive process in different ways and later on in life they may be involved in the propagation of prostate cancer.Exosomes can function in a multitude of processes, e.g. intercellular communication during immune response and they can indirectly stimulate the immune system. They are being used in clinical trials as tumour antigen bearers to trigger tumour rejection by the body.
Place, publisher, year, edition, pages
2007. Vol. 104, no 10, 784-786 p.
Exocytos, Sekretoriska blåsor, Cellkommunikation
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-102289PubMedID: 17432796OAI: oai:DiVA.org:uu-102289DiVA: diva2:214591