uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Distribution of neuroendocrine cells in the small and large intestines of the one-humped camel (Camelus dromedarius)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences.
Show others and affiliations
2007 (English)In: Neuropeptides, ISSN 0143-4179, E-ISSN 1532-2785, Vol. 41, no 5, 293-299 p.Article in journal (Refereed) Published
Abstract [en]

The distribution and relative frequency of neuroendocrine cells in the small and large intestines of one-humped camel were studied using antisera against 5-hydroxytryptamine (5-HT), cholecystokinin (CCK-8), somatostatin (SOM), peptide tyrosine tyrosine (PYY), gastric inhibitory polypeptide (GIP), neuronal nitric oxide synthase (nNOS), gastrin releasing peptide (GRP), substance P (SP), and neurokinin A (NKA). Among these cell types, CCK-8 immunoreactive (IR) cells were uniformly distributed in the mucosa, while others showed varied distribution in the villi or crypts of the small intestine. Immunoreactive cells like 5HT, CCK-8, and SOM showed peak density in the villi and crypts of the small intestine and in the colonic glands of the large intestine, while cells containing SP were discerned predominately in the crypts. 5-HT, CCK-8 and SOM cells were mainly flask-shaped and of the open-variety, while PYY and SP immunoreactive cells were mainly rounded or basket-shaped and of the closed variety. Basically the distribution pattern of the endocrine cells in the duodenum, jejunum and colon of the one-humped camel is similar to that of other mammals. Finally, the distribution of these bioactive agents may give clues as to how these agents aid in the function of the intestinal tract of this desert animal.

Place, publisher, year, edition, pages
2007. Vol. 41, no 5, 293-299 p.
Keyword [en]
Camel, Duodenum, Jejunum, Colon, Neuroendocrine cells, Immunohistochemistry
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-102861DOI: 10.1016/j.npep.2007.05.005ISI: 000249637900003PubMedID: 17688943OAI: oai:DiVA.org:uu-102861DiVA: diva2:216915
Available from: 2009-05-12 Created: 2009-05-12 Last updated: 2011-01-24Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed
By organisation
Department of Pharmaceutical Biosciences
In the same journal
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 210 hits
ReferencesLink to record
Permanent link

Direct link