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Taking due care: Moral obligations in dual use research
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Centre for Research Ethics and Bioethics.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Centre for Research Ethics and Bioethics.ORCID iD: 0000-0001-7486-4678
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Centre for Research Ethics and Bioethics.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Centre for Research Ethics and Bioethics.
2008 (English)In: Bioethics, ISSN 0269-9702, E-ISSN 1467-8519, Vol. 22, no 9, 477-487 p.Article in journal (Refereed) Published
Abstract [en]

In the past decade, the perception of a bioterrorist threat has increased and created a demand on life scientists to consider the potential security implications of dual use research. This article examines a selection of proposed moral obligations for life scientists that have emerged to meet these concerns and the extent to which they can be considered reasonable. It also describes the underlying reasons for the concerns, how they are managed, and their implications for scientific values.Five criteria for what constitutes preventable harm are suggested and a number of proposed obligations for life scientists are considered against these criteria, namely, the obligations to prevent bioterrorism; to engage in response activities; to consider negative implications of research; not to publish or share sensitive information; to oversee and limit access to dangerous material; and to report activities of concern.

Although bioterrorism might be perceived as an imminent threat, the analysis illustrates that this is beyond the responsibility of life scientists either to prevent or to respond to. Among the more reasonable obligations are duties to consider potential negative implications of one's research, protect access to sensitive material, technology and knowledge, and report activities of concern. Responsibility, therefore, includes obligations concerned with preventing foreseeable and highly probable harm. A central conclusion is that several of the proposed obligations are reasonable, although not unconditionally.

Place, publisher, year, edition, pages
2008. Vol. 22, no 9, 477-487 p.
Keyword [en]
bioethics, biological weapons, dual use, duty, obligation, research ethics
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-102990DOI: 10.1111/j.1467-8519.2008.00695.xISI: 000260048200004PubMedID: 18959730OAI: oai:DiVA.org:uu-102990DiVA: diva2:217156
Available from: 2009-05-13 Created: 2009-05-13 Last updated: 2017-03-30
In thesis
1. Responsible Conduct in Dual Use Research: Towards an Ethic of Deliberation in the Life Sciences
Open this publication in new window or tab >>Responsible Conduct in Dual Use Research: Towards an Ethic of Deliberation in the Life Sciences
2013 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Life scientists have increasingly been asked to incorporate a dual use responsibility in their research conduct. In this thesis, different aspects of what constitutes a reasonable responsibility in terms of avoiding harmful misuse of research for biological weapon purposes have been explored.

The first study investigated the claim that scientists have a dual use responsibility, and also outlined some of its possible content. Criteria for what may constitute preventable harm were used to analyze some proposed obligations in the field, and it was concluded that reasonable obligations include: e.g. considering the potential negative implications of one’s research and reporting activities of concern. In the second study, the conditions for a Precautionary Principle (PP) were explored and applied to the dual use research context. The study found that the main conditions of the PP frequently appear in present discussions and formulations of life scientists’ responsibility. It was also concluded that the PP is applicable to the dual use field and that it is meaningful and useful as a normatively guiding principle. The third study suggested an ethics of dissemination, based on the assumption that scientists have a responsibility to occasionally constrain the dispersion of their research findings. Three core aspects were proposed for an ethics of dual use dissemination. Additionally, to help scientists understand when constraints may be justified, three corresponding conditions for their application were suggested. In the fourth study, the concept of ethical competence was introduced and explored within a dual use context. It was concluded that competence-building is important in the nurturing of individual responsibility and, subsequently, in achieving a culture of dual use responsibility in the life sciences.

Finally, the discussion on ethical competence was included in a proposed ethic of deliberation, in which various stakeholders in the dual use debate are conceived to participate in communicative processes. It was argued that spaces for deliberative activities should be institutionalized by the scientific community to ensure structural opportunities for individuals to both assume responsibility and share it. Moreover, it was argued that deliberation can constitute a cornerstone of responsible dual use governance.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2013. 95 p.
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 1651-6206 ; 866
Keyword
bioethics, biological warfare, biological weapons, biosecurity, communicative ethics, deliberative ethics, dual use, ethical competence, life science research, precautionary principle, responsible conduct
National Category
Medical Ethics
Research subject
Bioethics
Identifiers
urn:nbn:se:uu:diva-193050 (URN)978-91-554-8593-1 (ISBN)
Public defence
2013-03-23, Auditorium Minus, Gustavianum, Akademigatan 3, Uppsala, 09:15 (English)
Opponent
Supervisors
Available from: 2013-03-01 Created: 2013-01-28 Last updated: 2013-03-05Bibliographically approved

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Eriksson, StefanHöglund, Anna T.

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