uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Bone healing of severe acetabular defects after revision arthroplasty
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Orthopaedics. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Research and Development, Gävleborg.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Section of Nuclear Medicine and PET.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Orthopaedics.
2009 (English)In: Acta Orthopaedica, ISSN 1745-3674, E-ISSN 1745-3682, Vol. 80, no 2, 179-183 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND AND PURPOSE: Healing of acetabular bone grafts may be difficult to assess in conventional radiographs. We used PET to analyze healing of morselized bone allografts, impacted in large osteolytic acetabular defects at revision arthroplasty. PATIENTS AND METHODS: 7 cases had a cup revision because of loosening, with repair of a segmental defect using a perforated, wide and thin plate. The osteolytic acetabulum was impacted with morselized bone allograft before cementing a polyethylene cup. [(18)F]-fluoride PET scans were used to monitor bone healing inside the graft bed 1 week, 4 weeks, and 12 months after surgery. The contralateral pelvic bone above the acetabulum was used as reference. A second group of 4 cases was analyzed for bone-forming activity in the state of mechanical loosening of an acetabular component of a THA. RESULTS: Preoperatively, the uptake was raised by 64% compared to the reference. 1 week after surgery it was increased by 77% in segmental regions, while the uptake was at the reference level in cavitary regions. After 4 months the uptake was increased by 91% in cavitary regions and by 117% in segmental regions. 1 year after surgery, the increase in uptake was 20% in both regions. All implants were stable on radiographs. INTERPRETATION: We found PET to be a sensitive and useful method for evaluation of the spatial and temporal development of bone formation.

Place, publisher, year, edition, pages
2009. Vol. 80, no 2, 179-183 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-103167DOI: 10.3109/17453670902947416ISI: 000265628700008PubMedID: 19404799OAI: oai:DiVA.org:uu-103167DiVA: diva2:217625
Available from: 2009-05-15 Created: 2009-05-15 Last updated: 2017-12-13Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Authority records BETA

Sörensen, JensNilsson, Olle

Search in DiVA

By author/editor
Sörensen, JensNilsson, Olle
By organisation
OrthopaedicsCentre for Research and Development, GävleborgDepartment of Medical SciencesSection of Nuclear Medicine and PET
In the same journal
Acta Orthopaedica
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 437 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf