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Neuropeptide phylogeny and evolution
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience. (Larhammar)
2009 (English)In: Encyclopedia of Neuroscience / [ed] Larry R. Squire, Oxford: Academic Press , 2009, 873-879 p.Chapter in book (Other academic)
Abstract [en]

Neuropeptides constitute a huge class of signaling molecules in the nervous system of many groups of animals. The phylogenetic relationships of neuropeptides have been difficult to determine across distantly related phyla because of their short amino acid sequences. Nevertheless, several neuropeptides are now known to have originated before the divergence of protostomes and deuterostomes. Many neuropeptides belong to families that have expanded by tandem duplications within a single gene or by gene duplications. Most neuropeptides act through G-protein-coupled receptors and the diversity and relationships of neuropeptides is also reflected in the multiplicity and relationships of their receptors.

Place, publisher, year, edition, pages
Oxford: Academic Press , 2009. 873-879 p.
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Medical and Health Sciences
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URN: urn:nbn:se:uu:diva-105030DOI: 10.1016/B978-008045046-9.01463-7ISBN: 978-0-08-045046-9 (print)OAI: oai:DiVA.org:uu-105030DiVA: diva2:220362
Available from: 2009-05-31 Created: 2009-05-31 Last updated: 2010-12-07Bibliographically approved

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