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Indication of peripheral nerve hyperexcitability in adult-onset subacute sclerosing panencephalitis (SSPE)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Clinical Neurophysiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Clinical Neurophysiology.
2008 (English)In: Neurological Sciences, ISSN 1590-1874, E-ISSN 1590-3478, Vol. 29, no 2, 121-124 p.Article in journal (Refereed) Published
Abstract [en]

Subacute sclerosing panencephalitis (SSPE) is a rare chronic, progressive encephalitis that affects primarily children and young adults, caused by a persistent infection of immune-resistant measles virus. Diagnostic hallmarks include widespread cortical dysfunction on EEG, myoclonus, white matter abnormalities on neuroradiological examination and the presence of IgG antimeasles antibodies in the cerebrospinal fluid. We present the first case of SSPE with signs of peripheral nerve hyperexcitability, observed as extra discharges following the compound motor action potential at motor nerve stimulation. In addition we demonstrate the importance of SSPE in the differential diagnosis of adult patients with psychiatric and neurological symptoms.

 

Place, publisher, year, edition, pages
2008. Vol. 29, no 2, 121-124 p.
Keyword [en]
SSPE, peripheral, nerve, hyperexcitability, extra discharges
Identifiers
URN: urn:nbn:se:uu:diva-105070DOI: 10.1007/s10072-008-0872-yISI: 000255789400010PubMedID: 18483711OAI: oai:DiVA.org:uu-105070DiVA: diva2:220471
Available from: 2009-06-01 Created: 2009-06-01 Last updated: 2014-09-01Bibliographically approved

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Stålberg, Erik V.Rostedt Punga, Anna

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