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The importance of rectal cancer MRI protocols on interpretation accuracy
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology, Radiology.
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2008 (English)In: World journal of surgical oncology, ISSN 1477-7819, Vol. 6, 89- p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Magnetic resonance imaging (MRI) is used for preoperative local staging in patients with rectal cancer. Our aim was to retrospectively study the effects of the imaging protocol on the staging accuracy. PATIENTS AND METHODS: MR-examinations of 37 patients with locally advanced disease were divided into two groups; compliant and noncompliant, based on the imaging protocol, without knowledge of the histopathological results. A compliant rectal cancer imaging protocol was defined as including T2-weighted imaging in the sagittal and axial planes with supplementary coronal in low rectal tumors, alongside a high-resolution plane perpendicular to the rectum at the level of the primary tumor. Protocols not complying with these criteria were defined as noncompliant. Histopathological results were used as gold standard. RESULTS: Compliant rectal imaging protocols showed significantly better correlation with histopathological results regarding assessment of anterior organ involvement (sensitivity and specificity rates in compliant group were 86% and 94%, respectively vs. 50% and 33% in the noncompliant group). Compliant imaging protocols also used statistically significantly smaller voxel sizes and fewer number of MR sequences than the noncompliant protocols CONCLUSION: Appropriate MR imaging protocols enable more accurate local staging of locally advanced rectal tumors with less number of sequences and without intravenous gadolinium contrast agents.

Place, publisher, year, edition, pages
2008. Vol. 6, 89- p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-105131DOI: 10.1186/1477-7819-6-89ISI: 000260650400002PubMedID: 18715510OAI: oai:DiVA.org:uu-105131DiVA: diva2:220536
Available from: 2009-06-01 Created: 2009-06-01 Last updated: 2012-03-07Bibliographically approved

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Torkzad, Michael R.
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