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What can we learn about asthma and allergy from the follow-up of the RHINE and the ECRHS studies?
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Respiratory Medicine and Allergology.
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2008 (English)In: Clinical Respiratory Journal, ISSN 1752-6981, Vol. 2, no 1, 45-52 p.Article, review/survey (Refereed) Published
Abstract [en]

Object: The international population-based studies RHINE and ECRHS have provided new insight in the epidemiology and management of asthma, allergy and rhinitis in young adults. The aim of the present review is to focus on longitudinal results with regard incidence and net change of asthma and asthma-like symptoms, risk factors and management of asthma, with special reference to the Nordic-Baltic countries.

Results: Asthma and rhinitis are common conditions that are important in a public health perspective. There are gender differences in incidence and remission. A socio-economic gradient that non-atopic asthma is more strongly related to poverty seems to have developed in the last decade. These findings will challenge our welfare states in the future. In addition, occupational, as well as indoor and outdoor environmental exposures, influenced the onset of asthma. The population-attributable risk for adult asthma because of occupational exposures is equivalent to an incidence of new-onset asthma of 250–300 cases per million per year. Genetic factors, allergic sensitisation, gastro-oesophageal reflux, habitual snoring, diet and other factors may also contribute to the onset of asthma and rhinitis. Even though management of asthma has improved, there are still great variations throughout Europe. These findings highlight the key role doctors and nurses play in educating and reviewing management of patients.

Place, publisher, year, edition, pages
2008. Vol. 2, no 1, 45-52 p.
Keyword [en]
Allergy, asthma, cohort studies, population-based studies
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-106122DOI: 10.1111/j.1752-699X.2008.00083.xISI: 000259610500006OAI: oai:DiVA.org:uu-106122DiVA: diva2:223925
Conference Information: Workshop on Respiratory Epidemiologic Research Lofoten, NORWAY, AUG 18-21, 2007 Available from: 2009-06-15 Created: 2009-06-15 Last updated: 2011-03-21Bibliographically approved

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Janson, Christer
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