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Nutritional supplementation and dietary advice in geriatric patients at risk of malnutrition.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences.
2007 (English)In: Clinical Nutrition, ISSN 0261-5614, E-ISSN 1532-1983, Vol. 26, no 2, 216-224 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND & AIM: Effects of combined nutritional treatment of patients at risk of protein-energy malnutrition (PEM) discharged from a geriatric service were evaluated. METHODS: Patients (n=108, age 85+/-6 years) at risk of malnutrition according to the short form of the mini nutritional assessment were randomly allocated to dietary counseling, including liquid and multivitamin supplementation, i.e. intervention (I, n=51) and to controls (C, n=57). Body weight, biochemical indices (e.g. insulin-like growth factor I (IGF-I)), Katz activities of daily living (ADL) index, mini mental status examination (MMSE) and quality of life (QoL) by SF-36 were assessed at the start of the study and after 4 months. Statistical analyses were performed on "intention-to-treat" and on "treated-as-protocol" bases. RESULTS: Fifty-four patients, 29 in the I-group (86+/-7 years, 66% females) and 25 in the C-group (85+/-7 years, 72% females) completed the study according to the protocol. Both modes of analysis revealed a significant positive effect of the combined nutritional intervention on weight maintenance. Treated-as-protocol analyses showed that Katz ADL index improved in the I-group (p<0.001; p<0.05 between the groups). Serum IGF-I levels increased in the I-group (p<0.001), but were unchanged in the C-group (p=0.07 between the groups). QoL was assessed to be low and had not changed after nutritional treatment. CONCLUSIONS: Combined nutritional intervention prevented weight loss and improved ADL functions in discharged geriatric patients at risk of malnutrition.

Place, publisher, year, edition, pages
2007. Vol. 26, no 2, 216-224 p.
Keyword [en]
Protein-energy malnutrition, Aged, Activities of daily living, Quality of life, Insulin-like growth factor I
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-108944DOI: 10.1016/j.clnu.2006.12.002ISI: 000246333500005PubMedID: 17275141OAI: oai:DiVA.org:uu-108944DiVA: diva2:241671
Available from: 2009-10-05 Created: 2009-10-05 Last updated: 2011-04-11Bibliographically approved

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