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In vitro effects on bacterial growth of phenoloxidase reaction products
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Physiology and Developmental Biology, Comparative Physiology.
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Physiology and Developmental Biology, Comparative Physiology.
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Physiology and Developmental Biology, Comparative Physiology.
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Physiology and Developmental Biology, Comparative Physiology.
2010 (English)In: Journal of Invertebrate Pathology, ISSN 0022-2011, E-ISSN 1096-0805, Vol. 103, no 1, 21-23 p.Article in journal (Refereed) Published
Description
Abstract [en]

An active phenoloxidase preparation from the freshwater crayfish Pacifastacus leniusculus exhibited a strong antibacterial effect in vitro on the bacteria Aeromonas hydrophila, Escherichia coli, Streptococcus pneumoniae whereas a weaker but still significant effect against Bacillus cereus, Pseudomonas aeruginosa and Staphylococcus aureus. In most cases reduction of bacterial growth was stronger when dopamine was used as substrate as compared to L-dopa. The effect on bacteria was abolished if no substrate was available for the phenoloxidase or in the presence of the phenoloxidase inhibitor phenylthiourea.

Place, publisher, year, edition, pages
Elsevier , 2010. Vol. 103, no 1, 21-23 p.
Keyword [en]
innate immunity, prophenoloxidase, bacterial growth inhibition
National Category
Immunology
Research subject
Immunology
Identifiers
URN: urn:nbn:se:uu:diva-109087DOI: 10.1016/j.jip.2009.09.006ISI: 000273993000003OAI: oai:DiVA.org:uu-109087DiVA: diva2:248829
Available from: 2009-10-09 Created: 2009-10-09 Last updated: 2017-12-13Bibliographically approved

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Cerenius, LageSöderhäll, Kenneth

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