In vitro effects on bacterial growth of phenoloxidase reaction products
2010 (English)In: Journal of Invertebrate Pathology, ISSN 0022-2011, E-ISSN 1096-0805, Vol. 103, no 1, 21-23 p.Article in journal (Refereed) Published
An active phenoloxidase preparation from the freshwater crayfish Pacifastacus leniusculus exhibited a strong antibacterial effect in vitro on the bacteria Aeromonas hydrophila, Escherichia coli, Streptococcus pneumoniae whereas a weaker but still significant effect against Bacillus cereus, Pseudomonas aeruginosa and Staphylococcus aureus. In most cases reduction of bacterial growth was stronger when dopamine was used as substrate as compared to L-dopa. The effect on bacteria was abolished if no substrate was available for the phenoloxidase or in the presence of the phenoloxidase inhibitor phenylthiourea.
Place, publisher, year, edition, pages
Elsevier , 2010. Vol. 103, no 1, 21-23 p.
innate immunity, prophenoloxidase, bacterial growth inhibition
Research subject Immunology
IdentifiersURN: urn:nbn:se:uu:diva-109087DOI: 10.1016/j.jip.2009.09.006ISI: 000273993000003OAI: oai:DiVA.org:uu-109087DiVA: diva2:248829