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Effects of mode of oral iron administration on serum ferritin and haemoglobin in infants
Department of Clinical Sciences, Paediatrics, Umeå University, Sweden.
Department of Clinical Sciences, Paediatrics, Umeå University, Sweden.
Department of Nutrition, University of California, USA.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health. (Internationell barnhälsa och nutrition/Persson)
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2008 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 97, no 8, 1055-1060 p.Article in journal (Refereed) Published
Abstract [en]

Aim: To investigate effects of iron-fortified foods (FFs) and medicinal iron drops (MD) on iron status in infants.

Methods: Data from one MD and one FF study were compared. Infants were divided into groups depending on the predominant source and amount of dietary iron during 6–9 months of age: MD: Medicinal iron drops (1 mg/kg/day). FF: iron intake >1.3 mg/kg/day, predominantly from FF and no iron supplements. Low iron (LI) group: iron intake <1.3 mg/kg/day and no iron supplements.

Results: Mean iron intake did not differ between MD (n = 30) and FF (n = 35) groups but was lower in the LI (n = 232) group. The FF group had significantly higher mean Hb at 9 months compared to the MD and LI groups (120 vs. 115 g/L and 120 vs. 116 g/L, respectively, p ≤ 0.005). The MD group had significantly higher mean SF at 9 months compared to the FF and the LI groups (46 vs. 23 μg/L and 46 vs. 26 μg/L, respectively, p < 0.001).

Conclusions: Our results suggest that, in healthy, term, nonanaemic 6–9-month-old infants, iron given as medicinal iron drops is primarily deposited into iron stores while iron given as iron-fortified foods is primarily utilized for Hb synthesis.

Place, publisher, year, edition, pages
2008. Vol. 97, no 8, 1055-1060 p.
Keyword [en]
Drops, Ferritin, Fortified food, Haemoglobin, Iron
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-87184DOI: 10.1111/j.1651-2227.2008.00899.xISI: 000257700400013OAI: oai:DiVA.org:uu-87184DiVA: diva2:25331
Available from: 2008-11-27 Created: 2008-09-25 Last updated: 2017-12-13Bibliographically approved

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